Antiphospholipid syndrome and valvular heart disease, a complex scenario of thrombotic events, a case report.

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  • Additional Information
    • Source:
      Publisher: BioMed Central Country of Publication: England NLM ID: 101265113 Publication Model: Electronic Cited Medium: Internet ISSN: 1749-8090 (Electronic) Linking ISSN: 17498090 NLM ISO Abbreviation: J Cardiothorac Surg Subsets: MEDLINE
    • Publication Information:
      Original Publication: [London] : BioMed Central, 2006-
    • Subject Terms:
      Antiphospholipid Syndrome/*complications ; Aortic Valve Disease/*complications ; Heart Valve Prosthesis Implantation/*adverse effects ; Myocardial Infarction/*etiology; Adult ; Anticoagulants/therapeutic use ; Antiphospholipid Syndrome/drug therapy ; Aortic Valve Disease/surgery ; Computed Tomography Angiography ; Echocardiography ; Female ; Heart Arrest/etiology ; Humans ; Lupus Erythematosus, Systemic/complications ; Thrombosis/complications
    • Abstract:
      Background: Antiphospholipid syndrome (APS) is a rare coagulation disorder associated with thrombotic events, myocardial infarction, and valvular heart disease. During valvular replacement surgery, the high risk of thrombosis combined with the operative risks in these specific groups of patients poses a challenge to the medical team.
      Case Presentation: We present a case of a female patient with APS and mixed aortic valve disease. During surgery, she suddenly developed complete cardiac arrest. Three months later, after she recovered, and while she was still on close follow up, a thrombotic event caused myocardial infarction. After prompt and precise treatment, the patient successfully recovered; one year after surgery patient is doing well.
      Conclusion: Adequate surgical technique along with optimal anticoagulation strategies and long term follow up are of paramount importance to ensure an uneventful recovery. A multidisciplinary team is required to manage these complex scenarios and high-risk patients.
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    • Contributed Indexing:
      Keywords: Antiphospholipid syndrome; Aortic valve replacement; Coronaries arteries; Thrombus
    • Accession Number:
      0 (Anticoagulants)
    • Publication Date:
      Date Created: 20200930 Date Completed: 20210226 Latest Revision: 20240802
    • Publication Date:
      20240802
    • Accession Number:
      PMC7526220
    • Accession Number:
      10.1186/s13019-020-01330-9
    • Accession Number:
      32993710