IL-17A as a Potential Therapeutic Target for Patients on Peritoneal Dialysis.

Publisher: MDPI Country of Publication: Switzerland NLM ID: 101596414 Publication Model: Electronic Cited Medium: Internet ISSN: 2218-273X (Electronic) Linking ISSN: 2218273X NLM ISO Abbreviation: Biomolecules Subsets: MEDLINE

Original Publication: Basel, Switzerland : MDPI, 2011-

Peritoneal Dialysis*; Fibrosis/*genetics ; Interleukin-17/*genetics ; Renal Insufficiency, Chronic/*genetics; Dialysis Solutions/chemistry ; Fibrosis/pathology ; Humans ; Neovascularization, Pathologic/genetics ; Neovascularization, Pathologic/pathology ; Peritoneum/metabolism ; Peritoneum/pathology ; Renal Insufficiency, Chronic/pathology ; Renal Insufficiency, Chronic/therapy

Chronic kidney disease (CKD) is a health problem reaching epidemic proportions. There is no cure for CKD, and patients may progress to end-stage renal disease (ESRD). Peritoneal dialysis (PD) is a current replacement therapy option for ESRD patients until renal transplantation can be achieved. One important problem in long-term PD patients is peritoneal membrane failure. The mechanisms involved in peritoneal damage include activation of the inflammatory and immune responses, associated with submesothelial immune infiltrates, angiogenesis, loss of the mesothelial layer due to cell death and mesothelial to mesenchymal transition, and collagen accumulation in the submesothelial compact zone. These processes lead to fibrosis and loss of peritoneal membrane function. Peritoneal inflammation and membrane failure are strongly associated with additional problems in PD patients, mainly with a very high risk of cardiovascular disease. Among the inflammatory mediators involved in peritoneal damage, cytokine IL-17A has recently been proposed as a potential therapeutic target for chronic inflammatory diseases, including CKD. Although IL-17A is the hallmark cytokine of Th17 immune cells, many other cells can also produce or secrete IL-17A. In the peritoneum of PD patients, IL-17A-secreting cells comprise Th17 cells, γδ T cells, mast cells, and neutrophils. Experimental studies demonstrated that IL-17A blockade ameliorated peritoneal damage caused by exposure to PD fluids. This article provides a comprehensive review of recent advances on the role of IL-17A in peritoneal membrane injury during PD and other PD-associated complications.

Clinics (Sao Paulo). 2015 May;70(5):313-7. (PMID: 26039945)
Nephrol Dial Transplant. 2012 Mar;27(3):937-46. (PMID: 21856758)
Semin Dial. 2011 May-Jun;24(3):290-7. (PMID: 21682771)
Int J Environ Res Public Health. 2018 Dec 04;15(12):. (PMID: 30518032)
Curr Med Chem. 2006;13(22):2695-702. (PMID: 17017920)
Clin Exp Immunol. 2014 Nov;178(2):245-52. (PMID: 24996009)
Clin Chim Acta. 2014 Mar 20;430:109-14. (PMID: 24333488)
J Immunol. 2014 Apr 15;192(8):3697-708. (PMID: 24623128)
Expert Opin Biol Ther. 2019 Jan;19(1):45-54. (PMID: 30500317)
Exp Cell Res. 2011 Mar 10;317(5):685-90. (PMID: 21040721)
Sci Rep. 2016 Nov 07;6:36551. (PMID: 27819281)
J Immunol. 2000 Nov 15;165(10):5814-21. (PMID: 11067941)
Perit Dial Int. 2001 Mar-Apr;21(2):219-24. (PMID: 11330572)
Nat Rev Immunol. 2016 Mar;16(3):149-63. (PMID: 26875830)
Cell Immunol. 2020 Mar;349:104047. (PMID: 32019673)
Cytokine. 2016 Jan;77:238-44. (PMID: 26440138)
Infect Immun. 2013 Oct;81(10):3923-34. (PMID: 23918785)
Sci Rep. 2017 Mar 22;7:44941. (PMID: 28327551)
Immunity. 2001 Jun;14(6):705-14. (PMID: 11420041)
Dig Dis Sci. 2020 Jul;65(7):1971-1979. (PMID: 31808003)
J Leukoc Biol. 2002 Jan;71(1):1-8. (PMID: 11781375)
Biomed Res Int. 2015;2015:468574. (PMID: 26605330)
J Am Soc Nephrol. 2011 Sep;22(9):1682-95. (PMID: 21742730)
Int Urol Nephrol. 2018 Jun;50(6):1151-1161. (PMID: 29728994)
Front Immunol. 2020 Mar 12;11:348. (PMID: 32226427)
Perit Dial Int. 2007 May-Jun;27(3):283-7. (PMID: 17468476)
Arch Pathol Lab Med. 2006 Aug;130(8):1188-92. (PMID: 16879021)
PLoS One. 2014 Oct 03;9(10):e108477. (PMID: 25279459)
Perit Dial Int. 2016 Mar-Apr;36(2):129-34. (PMID: 26475848)
J Immunol. 2010 Apr 1;184(7):3336-40. (PMID: 20200272)
Mediators Inflamm. 2018 Dec 13;2018:2931049. (PMID: 30647531)
Kidney Int. 2007 Mar;71(6):514-25. (PMID: 17228364)
Mol Med Rep. 2019 Aug;20(2):1065-1074. (PMID: 31173199)
Scand J Immunol. 2013 Apr;77(4):230-7. (PMID: 23421430)
J Biol Chem. 2009 Mar 6;284(10):6038-42. (PMID: 19112107)
J Leukoc Biol. 2016 Sep;100(3):453-62. (PMID: 27034403)
Cochrane Database Syst Rev. 2014 Jun 23;(6):CD009120. (PMID: 24953826)
Am J Physiol Renal Physiol. 2017 Aug 1;313(2):F310-F318. (PMID: 28490530)
Perit Dial Int. 2001 Jan-Feb;21(1):85-8. (PMID: 11280504)
PLoS One. 2013 Dec 23;8(12):e85032. (PMID: 24376862)
Eur J Immunol. 2010 Jul;40(7):1927-37. (PMID: 20397212)
Cancer Lett. 2015 Apr 10;359(2):335-43. (PMID: 25641338)
Sci Rep. 2015 Nov 03;5:16053. (PMID: 26524953)
Perit Dial Int. 2003 Mar-Apr;23(2):116-22. (PMID: 12713076)
Front Physiol. 2018 Nov 26;9:1694. (PMID: 30534087)
Clin Sci (Lond). 2020 Mar 13;134(5):513-527. (PMID: 32104886)
Front Pharmacol. 2019 Jul 30;10:715. (PMID: 31417401)
Curr Med Chem. 2015;22(38):4341-65. (PMID: 26521930)
J Pathol. 2020 Jan;250(1):55-66. (PMID: 31579932)
Acta Medica (Hradec Kralove). 2010;53(2):73-7. (PMID: 20672742)
Cytokine Growth Factor Rev. 2010 Dec;21(6):463-9. (PMID: 21075042)
Mediators Inflamm. 2012;2012:912595. (PMID: 22547910)
Blood Purif. 2015;39(1-3):200-9. (PMID: 25765663)
Int J Artif Organs. 2005 Feb;28(2):164-9. (PMID: 15770593)
Dis Model Mech. 2008 Nov-Dec;1(4-5):264-74. (PMID: 19093035)
Nephron Exp Nephrol. 2011;117(4):e114-23. (PMID: 20924205)
Immunity. 2015 Dec 15;43(6):1040-51. (PMID: 26682981)
Pediatr Nephrol. 2017 Oct;32(10):1835-1843. (PMID: 27722783)
FEBS J. 2016 Jun;283(12):2309-25. (PMID: 27093550)
Mol Immunol. 2018 Feb;94:131-139. (PMID: 29306153)
Blood Purif. 1996;14(2):179-87. (PMID: 8785034)
Nephrol Dial Transplant. 2009 Dec;24(12):3669-76. (PMID: 19666665)
Kidney Int. 2011 Nov;80(9):915-925. (PMID: 21814171)
Cytokine. 2019 Aug;120:282-288. (PMID: 30772195)
Clin Exp Immunol. 2018 Jan;191(1):50-59. (PMID: 28945272)
Blood. 2003 Apr 1;101(7):2620-7. (PMID: 12411307)
N Engl J Med. 2004 Sep 23;351(13):1296-305. (PMID: 15385656)
Perit Dial Int. 2005 Jan-Feb;25(1):38-47. (PMID: 15770925)
J Thorac Oncol. 2012 Jul;7(7):1091-100. (PMID: 22534817)
Kidney Int Suppl (2011). 2011 Jun;1(1):2-5. (PMID: 25028622)
J Biol Chem. 2008 Jun 20;283(25):17003-8. (PMID: 18434325)
J Immunol. 2003 Feb 15;170(4):1958-63. (PMID: 12574364)
J Am Soc Nephrol. 2018 Apr;29(4):1210-1222. (PMID: 29483158)
Sci Rep. 2019 Dec 20;9(1):19582. (PMID: 31862905)
Kidney Int. 2016 Sep;90(3):515-24. (PMID: 27282936)
EMBO Mol Med. 2014 Dec 30;7(1):102-23. (PMID: 25550395)
J Am Soc Nephrol. 2010 Jul;21(7):1077-85. (PMID: 20448020)
Blood Purif. 2012;33(1-3):153-9. (PMID: 22269466)
Trends Mol Med. 2008 Jan;14(1):37-44. (PMID: 18068482)
Cytokine. 2015 Dec;76(2):260-269. (PMID: 26307557)
Atherosclerosis. 2014 Mar;233(1):291-9. (PMID: 24495792)
J Immunol. 2012 Apr 15;188(8):3573-83. (PMID: 22403442)
J Immunol. 2009 Dec 15;183(12):8167-75. (PMID: 20007582)
Perit Dial Int. 2005 Sep-Oct;25(5):483-91. (PMID: 16178483)
J Exp Med. 2013 Oct 21;210(11):2305-20. (PMID: 24101382)
J Neuroimmunol. 2012 Sep 15;250(1-2):9-17. (PMID: 22673299)
Neurochem Res. 2017 Oct;42(10):2831-2840. (PMID: 28600752)
Biomed Res Int. 2015;2015:416480. (PMID: 26064907)
Eur Cytokine Netw. 1999 Jun;10(2):219-26. (PMID: 10400828)
Front Genet. 2015 Jul 14;6:236. (PMID: 26236331)
Nephrol Dial Transplant. 2010 Jul;25(7):2209-17. (PMID: 20100727)
Blood. 2009 Jun 25;113(26):6611-8. (PMID: 19395673)
Immunol Lett. 2014 Jan-Feb;157(1-2):9-15. (PMID: 24269293)
Methods Mol Biol. 2017;1514:19-30. (PMID: 27787789)
Kidney Int. 2018 Aug;94(2):419-429. (PMID: 29776755)
Immunology. 2014 Oct;143(2):155-63. (PMID: 24689370)
J Clin Invest. 2014 Oct;124(10):4577-89. (PMID: 25180604)
J Am Soc Nephrol. 2009 Dec;20(12):2518-24. (PMID: 19820122)
J Am Soc Nephrol. 2011 Jan;22(1):21-7. (PMID: 21209251)
Protein Pept Lett. 2015;22(7):570-8. (PMID: 25990083)
PLoS One. 2012;7(2):e31492. (PMID: 22384029)
J Cell Mol Med. 2012 Aug;16(8):1934-45. (PMID: 22117756)
Adv Exp Med Biol. 2019;1165:285-303. (PMID: 31399970)
Infect Immun. 2013 Jan;81(1):182-8. (PMID: 23115041)
Res Vet Sci. 1991 Sep;51(2):180-4. (PMID: 1788481)
Kidney Int. 2017 Jul;92(1):179-191. (PMID: 28318629)
Kidney Int. 2010 Jul;78(1):23-8. (PMID: 20336052)
N Engl J Med. 2015 Dec 24;373(26):2534-48. (PMID: 26699169)
Eur J Clin Invest. 2017 Feb;47(2):137-148. (PMID: 28036114)
J Chin Med Assoc. 2011 Jan;74(1):11-5. (PMID: 21292197)
Gastroenterology. 2020 May;158(6):1745-1761. (PMID: 31982413)
Nat Rev Immunol. 2010 Jul;10(7):479-89. (PMID: 20559326)
PLoS One. 2014 Oct 02;9(10):e109628. (PMID: 25275561)
Biomed Pharmacother. 2018 Oct;106:1412-1418. (PMID: 30119214)
J Am Soc Nephrol. 2002 Feb;13(2):480-9. (PMID: 11805178)
Nat Rev Immunol. 2008 Dec;8(12):958-69. (PMID: 19029990)
Autoimmun Rev. 2020 Jan;19(1):102429. (PMID: 31734402)
Biochem Biophys Res Commun. 2011 Apr 8;407(2):348-54. (PMID: 21396350)
Front Biosci (Elite Ed). 2012 Jan 01;4:1478-95. (PMID: 22201969)
Nephron Exp Nephrol. 2014;126(1):1-7. (PMID: 24458092)
Br J Dermatol. 2016 Nov;175(5):892-901. (PMID: 27117954)
Trends Mol Med. 2016 Mar;22(3):230-241. (PMID: 26837266)
Cytokine. 2015 Jul;74(1):5-17. (PMID: 25458968)
J Immunol. 2007 Oct 1;179(7):4313-7. (PMID: 17878325)
Nat Rev Cardiol. 2020 Jul;17(7):387-401. (PMID: 32203286)
J Am Soc Nephrol. 2009 Mar;20(3):582-92. (PMID: 19158357)
Joint Bone Spine. 2017 May;84(3):327-334. (PMID: 27426446)
Cell Immunol. 2012;273(1):23-9. (PMID: 22192475)
J Am Soc Nephrol. 2014 Feb;25(2):209-11. (PMID: 24309186)
Fertil Steril. 2011 Jul;96(1):113-7. (PMID: 21601196)
Ren Fail. 2004 Jul;26(4):381-4. (PMID: 15462105)
J Vasc Res. 2011;48(1):52-8. (PMID: 20606471)
Nat Immunol. 2008 Jun;9(6):650-7. (PMID: 18454150)
J Cell Mol Med. 2014 Nov;18(11):2213-24. (PMID: 25164131)
Kidney Int. 2016 Mar;89(3):625-35. (PMID: 26880457)
Am J Physiol Renal Physiol. 2017 Mar 1;312(3):F385-F397. (PMID: 27852609)
J Immunol. 2008 May 15;180(10):6988-96. (PMID: 18453621)
Am J Kidney Dis. 2012 Dec;60(6):966-75. (PMID: 22835900)
Medicine (Baltimore). 2018 May;97(20):e10748. (PMID: 29768353)
J Immunol. 2011 Jul 1;187(1):490-500. (PMID: 21606249)
Int J Nephrol Renovasc Dis. 2018 Jun 11;11:173-186. (PMID: 29928142)
Mediators Inflamm. 2018 Oct 14;2018:5103672. (PMID: 30405320)
J Am Soc Nephrol. 2015 Jan;26(1):173-82. (PMID: 25012164)
Blood Purif. 2018;46(2):103-110. (PMID: 29672317)
Nat Rev Rheumatol. 2013 Jun;9(6):375-9. (PMID: 23229447)
Cancer Manag Res. 2018 Oct 04;10:4217-4228. (PMID: 30323677)
J Immunol. 2009 Sep 1;183(5):3259-67. (PMID: 19641141)
Mediators Inflamm. 2016;2016:3296307. (PMID: 27057095)
Arthritis Rheum. 2013 May;65(5):1347-56. (PMID: 23335253)
Mol Cell Biol. 2010 Oct;30(20):4877-89. (PMID: 20696842)
J Clin Invest. 2015 Mar 2;125(3):1069-80. (PMID: 25642768)
J Immunol. 2011 Sep 15;187(6):3003-14. (PMID: 21841134)
PLoS One. 2013 Apr 09;8(4):e60776. (PMID: 23585849)
J Cell Sci. 2010 Dec 15;123(Pt 24):4321-31. (PMID: 21098640)
Am J Respir Crit Care Med. 2011 Jul 1;184(1):37-49. (PMID: 21474648)
Blood Purif. 2012;34(1):48-57. (PMID: 22922738)
J Neuroimmunol. 2018 Nov 15;324:26-34. (PMID: 30205205)
FASEB J. 2019 Feb;33(2):3035-3050. (PMID: 30354670)
J Cell Physiol. 2019 Aug;234(8):12353-12368. (PMID: 30710341)
Lab Invest. 2013 Jul;93(7):812-24. (PMID: 23648563)
Am J Pathol. 2020 Jan;190(1):222-233. (PMID: 31654638)
PLoS One. 2015 Apr 24;10(4):e0120174. (PMID: 25910222)
Curr Hypertens Rep. 2016 Mar;18(3):21. (PMID: 26846785)
Int Immunopharmacol. 2013 Sep;17(1):1-8. (PMID: 23721689)
Rheumatology (Oxford). 2009 Dec;48(12):1491-7. (PMID: 19773408)
Ren Fail. 2017 Nov;39(1):406-412. (PMID: 28260396)
Front Pharmacol. 2019 Sep 13;10:1015. (PMID: 31572188)
Am J Kidney Dis. 2005 Nov;46(5):938-48. (PMID: 16253736)
J Exp Med. 2010 Mar 15;207(3):535-52. (PMID: 20176803)
Int J Inflam. 2012;2012:819467. (PMID: 22229105)
Nephrol Dial Transplant. 2011 Sep;26(9):2995-3005. (PMID: 21324976)
Kidney Int. 2010 Feb;77(4):319-28. (PMID: 19956083)
Hypertension. 2013 Dec;62(6):1068-73. (PMID: 24060899)
Trends Immunol. 2002 Nov;23(11):549-55. (PMID: 12401408)
N Engl J Med. 2003 Jan 30;348(5):403-13. (PMID: 12556543)
Am J Cancer Res. 2015 Feb 15;5(3):1169-79. (PMID: 26045995)
Nephrol Dial Transplant. 2006 Jul;21 Suppl 2:ii2-7. (PMID: 16825254)
Am J Kidney Dis. 2000 Apr;35(4):644-52. (PMID: 10739785)
PLoS One. 2014 Mar 05;9(3):e90399. (PMID: 24599047)
Int Immunol. 2009 May;21(5):511-22. (PMID: 19254958)
Nat Immunol. 2007 Feb;8(2):191-7. (PMID: 17136045)
Adv Perit Dial. 2003;19:186-90. (PMID: 14763059)
PLoS One. 2012;7(10):e46506. (PMID: 23056325)
Kidney Int Suppl. 2008 Apr;(108):S26-33. (PMID: 18379544)
N Engl J Med. 2015 Oct;373(14):1329-39. (PMID: 26422723)
Nature. 2012 Nov 29;491(7426):717-23. (PMID: 23051753)
Nat Rev Mol Cell Biol. 2019 Jan;20(1):21-37. (PMID: 30108335)
Perit Dial Int. 2006 Jan-Feb;26(1):53-63. (PMID: 16538876)
Biomolecules. 2020 Feb 07;10(2):. (PMID: 32046176)
Cytokine. 2019 Oct;122:154089. (PMID: 28663097)
Cytometry A. 2014 Jan;85(1):36-42. (PMID: 24009159)
Circ Res. 2017 Jan 6;120(1):229-243. (PMID: 28057795)
Semin Nephrol. 2017 Jan;37(1):54-65. (PMID: 28153195)
Br J Pharmacol. 2019 Jun;176(12):2002-2014. (PMID: 30270435)
JACC Basic Transl Sci. 2016 Dec;1(7):606-616. (PMID: 28280792)
J Am Soc Nephrol. 2013 Dec;24(12):2002-9. (PMID: 24179164)
Kidney Int. 2005 Sep;68(3):1303-11. (PMID: 16105065)
Proc Natl Acad Sci U S A. 2014 Aug 26;111(34):E3562-70. (PMID: 25114209)
Perit Dial Int. 2008 Nov;28 Suppl 5:S29-33. (PMID: 19008536)
J Leukoc Biol. 2005 Jul;78(1):14-26. (PMID: 15784687)
Perit Dial Int. 2009 Mar-Apr;29(2):227-30. (PMID: 19293361)
Lab Invest. 2010 Oct;90(10):1517-32. (PMID: 20531289)
PLoS Pathog. 2016 Nov 4;12(11):e1005952. (PMID: 27814401)
PLoS One. 2014 Sep 08;9(9):e106834. (PMID: 25197971)
Eur J Rheumatol. 2017 Dec;4(4):272-277. (PMID: 29308283)
Am J Kidney Dis. 2005 Aug;46(2):328-38. (PMID: 16112053)
Oncotarget. 2018 Jan 12;9(18):14397-14412. (PMID: 29581852)
J Clin Med. 2020 Jan 19;9(1):. (PMID: 31963845)
J Immunol. 2009 Mar 15;182(6):3884-91. (PMID: 19265168)
Biomed Res Int. 2015;2015:989560. (PMID: 26688823)
BMC Immunol. 2015 Sep 23;16:56. (PMID: 26400627)
FASEB J. 2017 Dec;31(12):5543-5556. (PMID: 28821630)
Discov Med. 2018 Dec;26(145):271-280. (PMID: 30695676)
Clin Exp Immunol. 2010 Dec;162(3):528-36. (PMID: 20964644)
Endocr Metab Immune Disord Drug Targets. 2009 Jun;9(2):178-86. (PMID: 19519466)
Nephrol Dial Transplant. 2011 Jul;26(7):2322-32. (PMID: 21098014)
PLoS One. 2016 Oct 21;11(10):e0165045. (PMID: 27768727)
Perit Dial Int. 1994;14(3):265-70. (PMID: 7948240)
J Heart Lung Transplant. 2012 Apr;31(4):419-26. (PMID: 22289485)
Int J Artif Organs. 2005 Feb;28(2):170-6. (PMID: 15770605)
Int J Mol Med. 2011 Sep;28(3):405-12. (PMID: 21537828)
Autoimmun Rev. 2019 Feb;18(2):129-136. (PMID: 30572135)
J Immunol. 2000 Nov 1;165(9):5269-77. (PMID: 11046061)
Cytokine. 2013 Nov;64(2):477-85. (PMID: 24011563)
J Nutr. 2001 Sep;131(9 Suppl):2515S-22S; discussion 2523S-4S. (PMID: 11533304)
Autoimmun Rev. 2017 Sep;16(9):984-991. (PMID: 28705781)
J Immunol. 2007 Apr 1;178(7):4466-72. (PMID: 17372004)
Arthritis Res Ther. 2014 Dec 31;16(6):4223. (PMID: 25551434)
Int J Mol Sci. 2013 May 17;14(5):10369-82. (PMID: 23685870)
Perit Dial Int. 2001;21 Suppl 3:S373-6. (PMID: 11887859)
Dis Markers. 2012;33(1):35-42. (PMID: 22710867)
Clin Cardiol. 2020 Apr;43(4):379-385. (PMID: 31872906)
Inflammation. 2008 Jun;31(3):167-79. (PMID: 18338242)
J Clin Hypertens (Greenwich). 2015 Oct;17(10):770-4. (PMID: 26140526)
Cell Immunol. 2015 Sep;297(1):33-9. (PMID: 26077826)
Anadolu Kardiyol Derg. 2009 Apr;9(2):75-83. (PMID: 19357047)
J Immunol. 2013 Aug 1;191(3):1364-72. (PMID: 23817417)
Immunopharmacol Immunotoxicol. 2011 Dec;33(4):667-75. (PMID: 21428710)
Am J Kidney Dis. 2007 Mar;49(3):452-61. (PMID: 17336707)
J Am Soc Nephrol. 2006 Dec;17(12):3447-57. (PMID: 17065241)
Cytokine. 2018 Jun;106:80-88. (PMID: 29111086)
Int Urol Nephrol. 2017 Jan;49(1):171-181. (PMID: 27722989)
Autoimmun Rev. 2014 Jun;13(6):668-77. (PMID: 24418308)
Emerg Microbes Infect. 2013 Sep;2(9):e60. (PMID: 26038490)
Nat Rev Nephrol. 2020 May;16(5):269-288. (PMID: 32060481)
Mol Med Rep. 2017 Apr;15(4):1786-1792. (PMID: 28259952)
Nature. 2008 May 8;453(7192):236-40. (PMID: 18368049)
Sci Rep. 2017 Jul 24;7(1):6229. (PMID: 28740213)
J Clin Invest. 2016 Jan;126(1):50-67. (PMID: 26595812)
Arthritis Res Ther. 2014 Jan 07;16(1):R4. (PMID: 24398084)
J Exp Med. 2009 Sep 28;206(10):2079-89. (PMID: 19737866)
Mol Med Rep. 2012 Jul;6(1):93-9. (PMID: 22552745)
Clin Cancer Res. 2013 Jun 15;19(12):3176-88. (PMID: 23616636)
Front Immunol. 2016 Jan 06;6:620. (PMID: 26779180)
Expert Opin Drug Saf. 2002 May;1(1):53-64. (PMID: 12904160)
Nat Med. 2019 May;25(5):805-813. (PMID: 31011203)
J Am Soc Nephrol. 2002 Feb;13(2):470-9. (PMID: 11805177)
Int J Artif Organs. 2005 Feb;28(2):156-63. (PMID: 15770604)
Immunol Res. 2008;41(3):165-74. (PMID: 18484192)
Biosci Rep. 2018 Jun 21;38(3):. (PMID: 29871973)
Clin J Am Soc Nephrol. 2009 Oct;4(10):1620-8. (PMID: 19729428)
Proc Natl Acad Sci U S A. 2009 Sep 1;106(35):14948-53. (PMID: 19706421)
Nephrol Dial Transplant. 2011 Nov;26(11):3722-8. (PMID: 21385862)
Perit Dial Int. 2015 Jan-Feb;35(1):14-25. (PMID: 25700459)
Front Vet Sci. 2018 Nov 28;5:291. (PMID: 30547040)
Mol Immunol. 2018 Dec;104:90-99. (PMID: 30448610)
Kidney Int. 2014 Aug;86(2):303-15. (PMID: 24552849)
Int Immunol. 2012 Mar;24(3):137-46. (PMID: 22207131)
Kidney Int. 2017 May;91(5):1088-1103. (PMID: 28065517)
J Am Heart Assoc. 2016 Sep 20;5(9):. (PMID: 27650878)
Artif Organs. 2010 Jul;34(7):E222-9. (PMID: 20545663)
Am J Transl Res. 2019 Mar 15;11(3):1473-1485. (PMID: 30972175)
Clin Exp Nephrol. 2015 Jun;19(3):336-42. (PMID: 24942605)
J Korean Med Sci. 2007 Dec;22(6):943-5. (PMID: 18162703)
Semin Immunopathol. 2019 May;41(3):283-297. (PMID: 30891627)
Adv Med. 2014;2014:473134. (PMID: 26556413)
Hypertension. 2014 Aug;64(2):305-14. (PMID: 24866139)
PLoS One. 2014 Sep 25;9(9):e108494. (PMID: 25254662)
Cochrane Database Syst Rev. 2013 Sep 11;(9):CD004289. (PMID: 24022428)
Nephrol Dial Transplant. 2010 Apr;25(4):1098-108. (PMID: 20067910)
Blood. 2010 Jan 14;115(2):335-43. (PMID: 19890092)
Hypertension. 2014 Mar;63(3):565-71. (PMID: 24366079)
Front Immunol. 2020 Feb 14;11:108. (PMID: 32117261)
Curr Opin Immunol. 2010 Apr;22(2):231-7. (PMID: 20144856)
J Am Soc Nephrol. 2016 Dec;27(12):3561-3576. (PMID: 27151919)
Front Immunol. 2018 Oct 16;9:2389. (PMID: 30386339)
Perit Dial Int. 2007 Jul-Aug;27(4):446-53. (PMID: 17602154)
Nephrology (Carlton). 2015 Sep;20(9):609-16. (PMID: 25881494)
Perit Dial Int. 2011 May-Jun;31(3):325-31. (PMID: 21357937)
Kidney Int. 2019 Jun;95(6):1418-1432. (PMID: 30982673)
Clin J Am Soc Nephrol. 2019 Jul 5;14(7):1100-1105. (PMID: 31068338)
Int J Clin Lab Res. 1991;21(2):152-8. (PMID: 1687725)
Biomed Res Int. 2018 Apr 4;2018:6415892. (PMID: 29850544)
Physiol Rev. 2017 Jul 1;97(3):1127-1164. (PMID: 28566539)
Cell Mol Gastroenterol Hepatol. 2020;9(4):661-677. (PMID: 31954178)
Immunol Rev. 2018 Mar;282(1):198-231. (PMID: 29431218)
Adv Perit Dial. 2009;25:50-5. (PMID: 19886317)
Arterioscler Thromb Vasc Biol. 2014 Dec;34(12):2658-68. (PMID: 25341795)
Curr Opin Investig Drugs. 2005 Mar;6(3):262-8. (PMID: 15816502)
Nephrology (Carlton). 2019 Oct;24(10):1081-1089. (PMID: 30887626)
Asian Pac J Trop Med. 2015 Sep;8(9):762-5. (PMID: 26433664)
Sci Rep. 2019 Feb 19;9(1):2264. (PMID: 30783187)
Clin Rev Allergy Immunol. 2018 Dec;55(3):379-390. (PMID: 30109481)
Blood. 2011 Jan 27;117(4):1250-9. (PMID: 21084709)
Cell. 2006 Sep 22;126(6):1121-33. (PMID: 16990136)
Perit Dial Int. 2008 Jun;28 Suppl 3:S83-7. (PMID: 18552271)
Perit Dial Int. 2010 May-Jun;30(3):294-9. (PMID: 20228178)

PI17/00119 to M.R-O, PI17/01495, DTS17/00203 and DTS19/00093 to J.E, PI16/02057, PI19/00815 to A.O, PI 15/00120 to R.S; PI18/0610 to J.M.V; and Red de Investigación Renal (REDINREN): RD16/0009 to M.R-O, A.O, R.S, J.M.V International Instituto de Salud Carlos III; PI17/00119 to M.R-O, PI17/01495, DTS17/00203 and DTS19/00093 to J.E, PI16/02057, PI19/00815 to A.O, PI 15/00120 to R.S; PI18/0610 to J.M.V; and Red de Investigación Renal (REDINREN): RD16/0009 to M.R-O, A.O, R.S, J.M.V International Fondos FEDER European Union; "NOVELREN" B2017/BMD-3751 to M.R-O, B2017/BMD-3686 CIFRA2-CM to A.O); International Comunidad de Madrid; FJCI-2016-29050 International the "Juan de la Cierva Formacion" training program of the Ministerio de Economia, Industria y Competitividad (MINECO) supported the salary of SR-M; EIN2019-103294 to M.R-O and SR-M International "Convocatoria Dinamización Europa Investigación 2019" MINECO; S.E.N. to M.R-O International Sociedad Española de Nefrologia; ERA-PerMed-JTC2018 (KIDNEY ATTACK AC18/00064 and PERSTIGAN AC18/00071) and DTS18/00032 to A.O; International ERA; Agreement No. 812699 to M.R.O. , M.L-C. and D.F. International IMPROVE-PD project ("Identification and Management of Patients at Risk-Outcome and Vascular Events in Peritoneal Dialysis") funding from the European Union's Horizon 2020 research and innovation program under the Marie Skłodowska-Curie Grant

Keywords: Interleukin-17A; chronic kidney disease; inflammation; membrane failure; mesothelial; pathology damage; peritoneal dialysis; renal

0 (Dialysis Solutions)
0 (IL17A protein, human)
0 (Interleukin-17)

Date Created: 20200929 Date Completed: 20210625 Latest Revision: 20210625

20231215

PMC7598617

10.3390/biom10101361

32987705