Technical Note: Fricke dosimetry for blood irradiators.

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  • Additional Information
    • Source:
      Publisher: John Wiley and Sons, Inc Country of Publication: United States NLM ID: 0425746 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2473-4209 (Electronic) Linking ISSN: 00942405 NLM ISO Abbreviation: Med Phys Subsets: MEDLINE
    • Publication Information:
      Publication: 2017- : Hoboken, NJ : John Wiley and Sons, Inc.
      Original Publication: Lancaster, Pa., Published for the American Assn. of Physicists in Medicine by the American Institute of Physics.
    • Subject Terms:
      Radiation Dosimeters* ; Radiometry*; Brazil ; Phantoms, Imaging
    • Abstract:
      Purpose: The Fricke dosimeter has been shown to be a viable option as an absorbed dose standard. This work aims to provide the dose distribution in an irradiator container during blood irradiation using Fricke dosimetry.
      Methods: Measurements were performed using a Gammacell Elan 3000 blood irradiator at Hemocenter in Rio de Janeiro, Brazil. A specific phantom was constructed and patented by the authors to perform these measurements. Fricke solution was prepared according to international protocols, and polyethylene bags filled with Fricke solution (n = 19) were spatially distributed within the phantom. Control bags were also submitted to the same process, except the irradiation. The irradiation time was calculated to give 25.7 Gy to the central portion of the phantom, the same dose used for blood bags.
      Results: Encouraging results were obtained with an overall uncertainty of 2.1% (k = 1). The obtained results were compared with the doses calculated by the physicist from Hemocenter based on parameters provided by the manufacturer. The mean dose delivered to the Fricke bag in the center of the phantom (cavity 2) was 28.7 ± 0.5 Gy, which is 12% higher than the planned dose of 25.7 Gy.
      Conclusions: The obtained results showed that the setup (Fricke and phantom) is able to perform dosimetry for blood irradiators. The delivered dose was higher than expected. This highlights the importance in controlling all the parameters during irradiation to ensure the correct dose for all irradiated bags.
      (© 2020 American Association of Physicists in Medicine.)
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    • Grant Information:
      Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ); Coordenação de Aperfeiçoamento de Pessoal de Nível Superior (CAPES)
    • Contributed Indexing:
      Keywords: Fricke dosimetry; Gammacell 3000 Elan; Irradiation process; TA-GVHD; blood irradiator dosimetry; chemical dosimeter
    • Publication Date:
      Date Created: 20200924 Date Completed: 20210514 Latest Revision: 20210514
    • Publication Date:
      20221213
    • Accession Number:
      10.1002/mp.14487
    • Accession Number:
      32970855