Shigella sonnei: virulence and antibiotic resistance.

Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0410427 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-072X (Electronic) Linking ISSN: 03028933 NLM ISO Abbreviation: Arch Microbiol Subsets: MEDLINE

Original Publication: Berlin, New York, Springer-Verlag.

Drug Resistance, Bacterial*; Dysentery, Bacillary/*drug therapy ; Dysentery, Bacillary/*microbiology ; Shigella sonnei/*drug effects ; Shigella sonnei/*pathogenicity; Anti-Bacterial Agents/pharmacology ; Ciprofloxacin/pharmacology ; Dysentery, Bacillary/diagnosis ; Dysentery, Bacillary/pathology ; Escherichia coli/drug effects ; Fluoroquinolones/pharmacology ; Humans ; Shigella flexneri/drug effects ; Type VI Secretion Systems/physiology

Shigella sonnei is the emerging pathogen globally, as it is the second common infectious species of shigellosis (bloody diarrhoea) in low- and middle-income countries (LMICs) and the leading one in developed world. The multifactorial processes and novel mechanisms have been identified in S. sonnei, that are collectively playing apart a substantial role in increasing its prevalence, while replacing the S. flexneri and other Gram-negative gut pathogens niche occupancy. Recently, studies suggest that due to improvement in sanitation S. sonnei has reduced cross-immunization from Plesiomonas shigelliodes (having same O-antigen as S. sonnei) and also found to outcompete the two major species of Enterobacteriaceae family (Shigella flexneri and Escherichia coli), due to encoding of type VI secretion system (T6SS). This review aimed to highlight S. sonnei as an emerging pathogen in the light of recent research with pondering aspects on its epidemiology, transmission, and pathogenic mechanisms. Additionally, this paper aimed to review S. sonnei disease pattern and related complications, symptoms, and laboratory diagnostic techniques. Furthermore, the available treatment reigns and antibiotic-resistance patterns of S. sonnei are also discussed, as the ciprofloxacin and fluoroquinolone-resistant S. sonnei has already intensified the global spread and burden of antimicrobial resistance. In last, prevention and controlling strategies are briefed to limit and tackle S. sonnei and possible future areas are also explored that needed more research to unravel the hidden mysteries surrounding S. sonnei.

N Engl J Med. 2014 Apr 17;370(16):1532-40. (PMID: 24738670)
J Microbiol Methods. 2018 Feb;145:14-19. (PMID: 29262293)
Foodborne Pathog Dis. 2011 Jan;8(1):11-7. (PMID: 20932087)
Epidemiol Infect. 2005 Feb;133(1):81-6. (PMID: 15724714)
Emerg Infect Dis. 2016 Sep;22(9):1545-53. (PMID: 27532625)
Cold Spring Harb Perspect Med. 2013 Oct 01;3(10):a016717. (PMID: 24086068)
J Clin Microbiol. 2016 Jun;54(6):1456-1461. (PMID: 26984974)
BMC Infect Dis. 2016 Nov 18;16(1):685. (PMID: 27863468)
mSphere. 2016 Dec 21;1(6):. (PMID: 28028547)
J Food Prot. 2003 Apr;66(4):535-41. (PMID: 12696674)
Infect Dis Poverty. 2020 Apr 17;9(1):39. (PMID: 32299485)
J Med Microbiol. 2006 Dec;55(Pt 12):1685-1691. (PMID: 17108272)
PLoS Pathog. 2015 Mar 20;11(3):e1004749. (PMID: 25794007)
BMC Infect Dis. 2014 May 15;14:260. (PMID: 24886028)
Infect Immun. 2012 Mar;80(3):1222-31. (PMID: 22202122)
Infect Dis Clin North Am. 2019 Dec;33(4):1105-1123. (PMID: 31668193)
Euro Surveill. 2015 Apr 16;20(15):. (PMID: 25953129)
Nat Rev Microbiol. 2017 Aug;15(8):450-451. (PMID: 28649137)
J Basic Microbiol. 2015 Apr;55(4):420-31. (PMID: 25557472)
Microb Genom. 2018 Apr;4(4):. (PMID: 29595412)
PLoS One. 2013 Dec 18;8(12):e82601. (PMID: 24367527)
Proc Natl Acad Sci U S A. 2000 Sep 12;97(19):10567-72. (PMID: 10954745)
J Antimicrob Chemother. 2016 Aug;71(8):2314-7. (PMID: 27246235)
FEMS Microbiol Ecol. 2012 Mar;79(3):581-93. (PMID: 22092755)
Paediatr Int Child Health. 2018 Nov;38(sup1):S50-S65. (PMID: 29790845)
Emerg Infect Dis. 2016 Nov;22(11):1948-1952. (PMID: 27767929)
Gut Pathog. 2018 Oct 24;10:47. (PMID: 30386437)
Clin Infect Dis. 2017 Nov 29;65(12):1974-1976. (PMID: 29053793)
Int J Antimicrob Agents. 2006 Mar;27(3):267-70. (PMID: 16455233)
Trans R Soc Trop Med Hyg. 2017 Jun 1;111(6):233-234. (PMID: 29044375)
Epidemiol Infect. 2013 Dec;141(12):2568-75. (PMID: 23425681)
Trends Microbiol. 2020 Aug;28(8):696-697. (PMID: 32663462)
BMC Res Notes. 2014 Feb 20;7:95. (PMID: 24555739)
Anaerobe. 2012 Oct;18(5):498-503. (PMID: 22967793)
Proc Natl Acad Sci U S A. 2016 Apr 26;113(17):4794-9. (PMID: 27078095)
Epidemiol Infect. 2013 Feb;141(2):233-41. (PMID: 22361246)
Mol Microbiol. 2012 Jul;85(1):107-21. (PMID: 22571618)
Curr Opin Infect Dis. 2018 Oct;31(5):449-454. (PMID: 30048255)
Mol Microbiol. 2007 Mar;63(6):1719-30. (PMID: 17367391)
Infect Immun. 2000 Oct;68(10):6056-61. (PMID: 10992522)
Emerg Infect Dis. 2004 Jun;10(6):1147-9. (PMID: 15207073)
Nat Rev Microbiol. 2007 Jul;5(7):540-53. (PMID: 17558427)
Front Immunol. 2015 May 07;6:219. (PMID: 25999954)
Infect Dis Clin North Am. 2018 Mar;32(1):19-34. (PMID: 29269192)
Front Cell Infect Microbiol. 2017 Mar 24;7:64. (PMID: 28393050)
Ann Rheum Dis. 2005 Apr;64(4):594-8. (PMID: 15550534)
Nat Commun. 2018 Apr 13;9(1):1462. (PMID: 29654279)
Trans R Soc Trop Med Hyg. 2017 Jun 1;111(6):255-260. (PMID: 29044373)
Emerg Infect Dis. 2007 Nov;13(11):1640-6. (PMID: 18217545)
Front Cell Infect Microbiol. 2017 May 30;7:229. (PMID: 28611956)
Lett Appl Microbiol. 2017 Jan;64(1):8-18. (PMID: 27783408)
Expert Rev Vaccines. 2009 Dec;8(12):1693-704. (PMID: 19943764)
Mil Med. 2017 Sep;182(S2):17-25. (PMID: 28885920)
J Clin Microbiol. 2004 May;42(5):2031-5. (PMID: 15131166)
Antimicrob Agents Chemother. 2015 Jan;59(1):152-8. (PMID: 25331695)
Clin Infect Dis. 2014 Oct;59(7):933-41. (PMID: 24958238)
J Med Microbiol. 2016 Aug;65(8):882-884. (PMID: 27302408)
Emerg Infect Dis. 2006 Sep;12(9):1458-60. (PMID: 17073105)
Lancet. 2018 Feb 24;391(10122):801-812. (PMID: 29254859)
Infect Drug Resist. 2019 Oct 07;12:3137-3167. (PMID: 31632102)
PLoS Negl Trop Dis. 2015 Jun 11;9(6):e0003708. (PMID: 26068698)
Gut Microbes. 2017 Nov 2;8(6):544-560. (PMID: 28598765)
J Microbiol. 2005 Apr;43(2):133-43. (PMID: 15880088)
J Antimicrob Chemother. 2017 Nov 01;72(11):3181-3186. (PMID: 28961759)
Nat Commun. 2019 Oct 23;10(1):4828. (PMID: 31645551)
Am J Epidemiol. 1991 Mar 15;133(6):608-15. (PMID: 2006648)
Ther Adv Vaccines. 2013 Sep;1(3):113-23. (PMID: 24757519)
Nat Rev Microbiol. 2009 Feb;7(2):99-109. (PMID: 19148178)
Clin Infect Dis. 2019 Oct 15;69(9):1535-1544. (PMID: 30615105)
Annu Rev Biochem. 2006;75:39-68. (PMID: 16756484)
J Food Prot. 2007 Jul;70(7):1704-9. (PMID: 17685346)
BMC Public Health. 2014 Sep 25;14:998. (PMID: 25257255)
J Immunol. 2014 Feb 15;192(4):1630-40. (PMID: 24453241)
BMC Infect Dis. 2013 Jul 30;13:354. (PMID: 23899288)
Epidemiol Infect. 2009 Mar;137(3):326-34. (PMID: 19134229)
Microbiol Res. 2011 Dec 20;167(1):27-31. (PMID: 21466951)
Cochrane Database Syst Rev. 2010 Aug 04;(8):CD006784. (PMID: 20687081)
J Pediatr Gastroenterol Nutr. 2012 Jan;54(1):136-60. (PMID: 22197856)
Arch Microbiol. 2009 Jan;191(1):83-8. (PMID: 18712360)
J Med Microbiol. 2008 Jul;57(Pt 7):856-863. (PMID: 18566144)
Eur J Epidemiol. 2001;17(6):533-8. (PMID: 11949725)
Semin Pediatr Infect Dis. 2004 Oct;15(4):246-52. (PMID: 15494948)
Emerg Infect Dis. 2016 Feb;23(2):345-346. (PMID: 28098533)
J Antimicrob Chemother. 2005 Mar;55(3):301-5. (PMID: 15681578)
Infect Immun. 2010 Apr;78(4):1682-91. (PMID: 20086081)
BMC Vet Res. 2018 Jun 7;14(1):177. (PMID: 29879965)
Lancet Infect Dis. 2015 Aug;15(8):913-21. (PMID: 25936611)
Gut Pathog. 2019 Jun 14;11:33. (PMID: 31249630)
Epidemiol Infect. 2009 Mar;137(3):335-41. (PMID: 18177516)
Int J Infect Dis. 2006 Nov;10(6):425-33. (PMID: 16997593)
J Clin Gastroenterol. 2009 Mar;43(3):208-13. (PMID: 18813028)
Mil Med. 2017 Sep;182(S2):4-10. (PMID: 28885918)
PLoS Med. 2016 Aug 02;13(8):e1002055. (PMID: 27483136)
Emerg Infect Dis. 2015 May;21(5):894-6. (PMID: 25897625)
Wien Klin Wochenschr. 2009;121(3-4):157-63. (PMID: 19280143)
J Antimicrob Chemother. 2016 Aug;71(8):2066-70. (PMID: 27342545)
Cell Host Microbe. 2017 Jun 14;21(6):769-776.e3. (PMID: 28618272)
Sci Total Environ. 2019 Jun 25;671:1206-1213. (PMID: 31186130)
J Biol Chem. 2008 Jul 4;283(27):18646-54. (PMID: 18450744)
Cell Host Microbe. 2011 Jun 16;9(6):508-19. (PMID: 21669399)
Indian J Med Res. 2016 May;143(5):565-76. (PMID: 27487999)
Int J Antimicrob Agents. 2012 Jul;40(1):9-17. (PMID: 22483324)
Appl Environ Microbiol. 2019 Mar 22;85(7):. (PMID: 30709819)
Antimicrob Agents Chemother. 1988 Oct;32(10):1598-9. (PMID: 3056243)
Lancet. 1997 Jan 18;349(9046):155-9. (PMID: 9111538)
mBio. 2019 Dec 17;10(6):. (PMID: 31848280)
Proc Natl Acad Sci U S A. 2014 Oct 7;111(40):E4254-63. (PMID: 25246571)
Diagn Microbiol Infect Dis. 2007 Aug;58(4):469-75. (PMID: 17509797)
Curr Opin Immunol. 2011 Aug;23(4):448-55. (PMID: 21763117)
Clin Infect Dis. 1999 Nov;29(5):1303-6. (PMID: 10524979)
Front Microbiol. 2012 Apr 02;3:110. (PMID: 22485109)
Int J Environ Res Public Health. 2018 Aug 24;15(9):. (PMID: 30149494)
Epidemiol Infect. 2015 Oct;143(13):2687-99. (PMID: 25553947)
Folia Microbiol (Praha). 2020 Apr;65(2):275-291. (PMID: 32026288)
J Travel Med. 2018 Jan 1;25(1):. (PMID: 30462260)
Vaccine. 2010 Feb 10;28(6):1642-54. (PMID: 19932216)
Mol Microbiol. 1998 Aug;29(3):677-84. (PMID: 9723908)
Immunol Cell Biol. 2015 Aug;93(7):641-52. (PMID: 25776843)
Int J Infect Dis. 2017 Jun;59:44-49. (PMID: 28392317)
Appl Environ Microbiol. 2018 Apr 16;84(9):. (PMID: 29475870)
Diagn Microbiol Infect Dis. 2003 Mar;45(3):173-81. (PMID: 12663158)
Front Cell Infect Microbiol. 2016 Apr 19;6:45. (PMID: 27148494)
Sci Rep. 2018 May 9;8(1):7389. (PMID: 29743642)
FEMS Microbiol Rev. 2008 Jul;32(4):627-53. (PMID: 18422615)
Nat Rev Microbiol. 2016 Apr;14(4):235-50. (PMID: 26923111)
Clin Infect Dis. 2018 Mar 5;66(6):963-969. (PMID: 29346620)
Trans R Soc Trop Med Hyg. 2013 Oct;107(10):631-8. (PMID: 24026463)
Front Cell Infect Microbiol. 2016 Mar 31;6:38. (PMID: 27066460)
Clin Microbiol Infect. 2015 Mar;21(3):252.e5-8. (PMID: 25658535)
BMC Res Notes. 2016 Aug 30;9(1):422. (PMID: 27576729)
Lancet Infect Dis. 2018 Nov;18(11):1229-1240. (PMID: 30266330)
Mol Microbiol. 2005 May;56(3):590-603. (PMID: 15819617)
PLoS Pathog. 2019 Dec 12;15(12):e1008006. (PMID: 31830135)
Commun Dis Intell Q Rep. 2012 Sep 30;36(3):E213-41. (PMID: 23186234)
Germs. 2017 Sep 1;7(3):115-122. (PMID: 28932711)
Nucleic Acids Res. 2005 Nov 07;33(19):6445-58. (PMID: 16275786)
Int J Antimicrob Agents. 2004 Aug;24(2):105-10. (PMID: 15288307)
EcoSal Plus. 2018 Jan;8(1):. (PMID: 29318984)
Front Cell Infect Microbiol. 2016 Apr 05;6:35. (PMID: 27092296)
Infect Chemother. 2020 Mar;52(1):123-131. (PMID: 32239814)
Nat Genet. 2012 Sep;44(9):1056-9. (PMID: 22863732)
Euro Surveill. 2009 Jun 18;14(24):. (PMID: 19555602)
Immunol Cell Biol. 2007 Feb-Mar;85(2):119-29. (PMID: 17213832)
Lancet Infect Dis. 2018 Mar;18(3):234-236. (PMID: 29276050)
Gastroenterol Hepatol Bed Bench. 2017 Summer;10(3):220-228. (PMID: 29118939)
Gut Pathog. 2017 May 8;9:28. (PMID: 28491143)
Cell Host Microbe. 2014 Apr 9;15(4):435-45. (PMID: 24721572)
Mol Microbiol. 2016 Feb;99(4):658-73. (PMID: 26481305)
Lett Appl Microbiol. 2011 Aug;53(2):247-51. (PMID: 21615433)
J Med Microbiol. 2013 Apr;62(Pt 4):499-513. (PMID: 23329317)

Keywords: Antimicrobial resistance; Escherichia coli; LMICs; Shigella flexneri; Shigella sonnei; Virulence

0 (Anti-Bacterial Agents)
0 (Fluoroquinolones)
0 (Type VI Secretion Systems)
5E8K9I0O4U (Ciprofloxacin)

Date Created: 20200915 Date Completed: 20210126 Latest Revision: 20240822

20240822

PMC7489455

10.1007/s00203-020-02034-3

32929595