Your blood pressure might be normal, but what about your podocytes?

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  • Author(s): Bertram JF;Bertram JF
  • Source:
    Kidney international [Kidney Int] 2020 Sep; Vol. 98 (3), pp. 545-547.
  • Publication Type:
    Journal Article; Comment
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: United States NLM ID: 0323470 Publication Model: Print Cited Medium: Internet ISSN: 1523-1755 (Electronic) Linking ISSN: 00852538 NLM ISO Abbreviation: Kidney Int Subsets: MEDLINE
    • Publication Information:
      Publication: 2016- : New York : Elsevier
      Original Publication: New York, Springer-Verlag.
    • Subject Terms:
      Hypertension, Renal* ; Nephritis* ; Nephrosclerosis* ; Podocytes*; Blood Pressure ; Humans
    • Abstract:
      Associations among hypertension, podocyte depletion, and chronic kidney disease are well-established, but whether mean arterial pressure (MAP) in the normal range influences podocyte depletion has not been previously examined. In this issue, Naik et al. use non-invasive urinary mRNA analysis to demonstrate that higher podocyte stress and detachment are associated with higher MAP in the normal range. The relationship between blood pressure and podocyte health suddenly got much more interesting.
      (Copyright © 2020 International Society of Nephrology. Published by Elsevier Inc. All rights reserved.)
    • Comments:
      Comment on: Am J Hypertens. 2009 Mar;22(3):300-6. (PMID: 19131934)
    • Publication Date:
      Date Created: 20200824 Date Completed: 20200923 Latest Revision: 20200923
    • Publication Date:
      20231215
    • Accession Number:
      10.1016/j.kint.2020.05.020
    • Accession Number:
      32828235