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Prognostic Markers of Myelodysplastic Syndromes.
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- Author(s): Veryaskina YA;Veryaskina YA; Titov SE; Titov SE; Titov SE; Kovynev IB; Kovynev IB; Pospelova TI; Pospelova TI; Zhimulev IF; Zhimulev IF
- Source:
Medicina (Kaunas, Lithuania) [Medicina (Kaunas)] 2020 Jul 27; Vol. 56 (8). Date of Electronic Publication: 2020 Jul 27.- Publication Type:
Journal Article; Review- Language:
English - Source:
- Additional Information
- Source: Publisher: MDPI Country of Publication: Switzerland NLM ID: 9425208 Publication Model: Electronic Cited Medium: Internet ISSN: 1648-9144 (Electronic) Linking ISSN: 1010660X NLM ISO Abbreviation: Medicina (Kaunas) Subsets: MEDLINE
- Publication Information: Publication: 2018- : Basel, Switzerland : MDPI
Original Publication: Kaunas : Lietuvos gydytojų sąjunga - Subject Terms: Prognosis*; Biomarkers/*analysis ; Myelodysplastic Syndromes/*diagnosis; Core Binding Factor Alpha 2 Subunit/analysis ; DNA (Cytosine-5-)-Methyltransferases/analysis ; DNA Methyltransferase 3A ; DNA-Binding Proteins/analysis ; Dioxygenases ; Humans ; Mutation/genetics ; Myelodysplastic Syndromes/genetics ; Myelodysplastic Syndromes/physiopathology ; Phosphoproteins/analysis ; Proto-Oncogene Proteins/analysis ; RNA Splicing Factors/analysis ; Repressor Proteins/analysis ; Serine-Arginine Splicing Factors/analysis
- Abstract: Myelodysplastic syndrome (MDS) is a clonal disease characterized by multilineage dysplasia, peripheral blood cytopenias, and a high risk of transformation to acute myeloid leukemia. In theory, from clonal hematopoiesis of indeterminate potential to hematologic malignancies, there is a complex interplay between genetic and epigenetic factors, including miRNA. In practice, karyotype analysis assigns patients to different prognostic groups, and mutations are often associated with a particular disease phenotype. Among myeloproliferative disorders, secondary MDS is a group of special entities with a typical spectrum of genetic mutations and cytogenetic rearrangements resembling those in de novo MDS. This overview analyzes the present prognostic systems of MDS and the most recent efforts in the search for genetic and epigenetic markers for the diagnosis and prognosis of MDS.
- References: Blood. 2019 Mar 7;133(10):1086-1095. (PMID: 30670443)
Blood. 2013 May 9;121(19):3811-7. (PMID: 23660859)
Oncol Rev. 2018 Dec 07;12(2):397. (PMID: 30607219)
Leukemia. 2013 Apr;27(4):957-9. (PMID: 23192014)
Leukemia. 2012 Feb;26(2):356-8. (PMID: 21799512)
Nature. 2006 Mar 23;440(7083):497-500. (PMID: 16554811)
Haematologica. 2011 Oct;96(10):1433-40. (PMID: 21659359)
Int J Mol Sci. 2016 May 30;17(6):. (PMID: 27248996)
Leukemia. 2018 Jul;32(7):1493-1499. (PMID: 29445113)
PLoS One. 2012;7(8):e42334. (PMID: 22912701)
Cancer Genet. 2013 Jan-Feb;206(1-2):42-6. (PMID: 23357231)
Cancer. 2012 Jan 1;118(1):127-33. (PMID: 21717439)
Yonsei Med J. 2016 Mar;57(2):358-64. (PMID: 26847287)
Blood. 2013 Dec 12;122(25):4021-34. (PMID: 24136165)
Exp Hematol Oncol. 2016 Apr 27;5:12. (PMID: 27127725)
Hematol Oncol. 2019 Oct;37(4):438-446. (PMID: 31378958)
Cancers (Basel). 2019 Sep 29;11(10):. (PMID: 31569513)
Hematology. 2019 Dec;24(1):60-69. (PMID: 30129389)
Oncotarget. 2017 Jan 24;8(4):6483-6495. (PMID: 28031539)
Blood Cells Mol Dis. 2018 Mar;69:90-100. (PMID: 29079134)
Int J Clin Oncol. 2019 Aug;24(8):885-892. (PMID: 31093808)
Leuk Res. 2015 Jul;39(7):763-8. (PMID: 25975751)
Int J Hematol. 2017 Jun;105(6):777-783. (PMID: 28224273)
Am J Hematol. 2012 Jul;87(7):659-62. (PMID: 22535592)
Leuk Res. 2014 Apr;38(4):447-53. (PMID: 24439566)
J Int Med Res. 2009 Jan-Feb;37(1):270-6. (PMID: 19215701)
Curr Opin Hematol. 2017 May;24(3):191-197. (PMID: 28072603)
Semin Oncol. 2005 Oct;32(5):521-30. (PMID: 16210093)
Leukemia. 2002 Dec;16(12):2366-78. (PMID: 12454741)
Genes Chromosomes Cancer. 2019 Oct;58(10):689-697. (PMID: 30994215)
J Clin Oncol. 2012 Apr 20;30(12):1343-9. (PMID: 22370328)
Hematology. 2016 Dec;21(10):593-602. (PMID: 27357100)
Nat Rev Cancer. 2017 Jan;17(1):5-19. (PMID: 27834397)
Leukemia. 2015 Jan;29(1):126-36. (PMID: 24781015)
Nat Genet. 2017 Feb;49(2):204-212. (PMID: 27992414)
Nat Genet. 2010 Aug;42(8):665-7. (PMID: 20601954)
Cancer Genet Cytogenet. 2010 Oct 15;202(2):108-22. (PMID: 20875873)
J Cancer. 2020 Jan 1;11(2):508-519. (PMID: 31897246)
Blood. 2004 May 1;103(9):3265-70. (PMID: 14684416)
Blood. 2011 Oct 27;118(17):4690-3. (PMID: 21868570)
Blood. 2019 Mar 7;133(10):1096-1107. (PMID: 30670446)
Cancer Genet. 2016 May;209(5):205-14. (PMID: 27134073)
PLoS One. 2014 Apr 01;9(4):e93404. (PMID: 24690917)
Br J Haematol. 2012 Jul;158(2):242-248. (PMID: 22533337)
Genes Chromosomes Cancer. 2000 Jan;27(1):11-6. (PMID: 10564581)
Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):277-285. (PMID: 30504322)
Semin Oncol. 2005 Aug;32(4 Suppl 5):S3-10. (PMID: 16085011)
Neoplasma. 2017;64(4):571-578. (PMID: 28485163)
Am Soc Clin Oncol Educ Book. 2019 Jan;39:400-410. (PMID: 31099654)
Leukemia. 2015 Jul;29(7):1502-13. (PMID: 25721895)
Blood. 2003 Jul 1;102(1):43-52. (PMID: 12623843)
Oncol Rev. 2019 Feb 04;13(1):389. (PMID: 30858933)
Leukemia. 2011 Jan;25(1):110-20. (PMID: 20882045)
Case Rep Oncol Med. 2014;2014:949515. (PMID: 24716056)
Semin Oncol. 2013 Dec;40(6):666-75. (PMID: 24331189)
N Engl J Med. 2012 Mar 22;366(12):1090-8. (PMID: 22417201)
Mutat Res Rev Mutat Res. 2016 Jul-Sep;769:47-62. (PMID: 27543316)
Blood Cancer J. 2018 Apr 4;8(4):39. (PMID: 29618722)
Haematologica. 2009 Dec;94(12):1762-6. (PMID: 19797731)
Br J Haematol. 2014 Mar;164(6):822-33. (PMID: 24372512)
Transfusion. 2017 Apr;57(4):1052-1057. (PMID: 28185276)
Leukemia. 2016 Apr;30(4):980-4. (PMID: 26228814)
Nature. 2011 Sep 11;478(7367):64-9. (PMID: 21909114)
Cancer. 2011 Dec 15;117(24):5529-37. (PMID: 21638279)
Leuk Lymphoma. 2019 Nov;60(11):2779-2786. (PMID: 31056984)
Leukemia. 2010 May;24(5):1062-5. (PMID: 20182461)
Cancer Genet Cytogenet. 2001 Oct 15;130(2):160-5. (PMID: 11675138)
Leukemia. 2017 Jun;31(6):1391-1397. (PMID: 28111463)
Case Rep Genet. 2018 Sep 9;2018:8296478. (PMID: 30271640)
Hematology. 2019 Dec;24(1):613-622. (PMID: 31482762)
Blood. 2011 Dec 8;118(24):6239-46. (PMID: 21998214)
Blood. 2016 May 19;127(20):2391-405. (PMID: 27069254)
J Clin Oncol. 2005 Jun 20;23(18):4179-91. (PMID: 15961765)
Mod Pathol. 2015 Mar;28(3):373-82. (PMID: 25216221)
Medicine (Baltimore). 2019 Jan;98(1):e14011. (PMID: 30608448)
Arch Pathol Lab Med. 2008 Aug;132(8):1329-32. (PMID: 18684036)
Leukemia. 2019 Jul;33(7):1747-1758. (PMID: 30635634)
Case Rep Hematol. 2015;2015:318545. (PMID: 26798525)
J Clin Oncol. 2012 Mar 10;30(8):820-9. (PMID: 22331955)
Leukemia. 2016 Nov;30(11):2214-2220. (PMID: 27311933)
Haematologica. 2017 Mar;102(3):498-508. (PMID: 27884971)
Leuk Res. 2011 Mar;35(3):351-7. (PMID: 20691474)
Leukemia. 2014 Feb;28(2):241-7. (PMID: 24220272)
Br J Haematol. 1982 Jun;51(2):189-99. (PMID: 6952920)
Leuk Res. 2015 Mar;39(3):348-54. (PMID: 25573287)
Blood. 2012 Apr 12;119(15):3578-84. (PMID: 22389253)
Haematologica. 2012 Dec;97(12):1845-9. (PMID: 22689682)
Blood. 2007 Dec 15;110(13):4385-95. (PMID: 17726160)
Nat Commun. 2019 Nov 26;10(1):5386. (PMID: 31772163)
Leukemia. 2010 Apr;24(4):740-7. (PMID: 20072149)
Mediterr J Hematol Infect Dis. 2015 May 01;7(1):e2015034. (PMID: 25960862)
N Engl J Med. 2009 May 28;360(22):2289-301. (PMID: 19474426)
Leuk Res. 2019 Nov;86:106227. (PMID: 31557598)
Leuk Res. 2006 Aug;30(8):971-7. (PMID: 16423393)
Leukemia. 2017 Mar;31(3):534-542. (PMID: 27899806)
Blood. 2017 Jun 22;129(25):3371-3378. (PMID: 28424163)
Exp Cell Res. 2014 Dec 10;329(2):234-8. (PMID: 25192911)
Blood. 1997 Mar 15;89(6):2079-88. (PMID: 9058730)
Crit Rev Oncol Hematol. 2020 Jan;145:102832. (PMID: 31812130)
Dtsch Arztebl Int. 2018 Dec 14;115(50):848-854. (PMID: 30722840)
Nat Genet. 2011 Dec 11;44(1):53-7. (PMID: 22158538)
Leukemia. 2011 Feb;25(2):266-70. (PMID: 21072042) - Grant Information: 19-34-60024 Russian Foundation for Basic Research
- Contributed Indexing: Keywords: IPSS-R; acute myeloid leukemia; karyotype; microRNA; myelodysplastic syndrome
- Accession Number: 0 (ASXL1 protein, human)
0 (Biomarkers)
0 (Core Binding Factor Alpha 2 Subunit)
0 (DNA-Binding Proteins)
0 (DNMT3A protein, human)
0 (Phosphoproteins)
0 (Proto-Oncogene Proteins)
0 (RNA Splicing Factors)
0 (RUNX1 protein, human)
0 (Repressor Proteins)
0 (SF3B1 protein, human)
147153-65-9 (SRSF2 protein, human)
170974-22-8 (Serine-Arginine Splicing Factors)
EC 1.13.11.- (Dioxygenases)
EC 1.13.11.- (TET2 protein, human)
EC 2.1.1.37 (DNA (Cytosine-5-)-Methyltransferases)
EC 2.1.1.37 (DNA Methyltransferase 3A) - Publication Date: Date Created: 20200731 Date Completed: 20210318 Latest Revision: 20211204
- Publication Date: 20231215
- Accession Number: PMC7466347
- Accession Number: 10.3390/medicina56080376
- Accession Number: 32727068
- Source:
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