[Myocardial blood flow and glucose metabolism in patients with myocardial infarction evaluated by positron emission tomography: comparison with left ventriculography].

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8804703 Publication Model: Print Cited Medium: Print ISSN: 0914-5087 (Print) Linking ISSN: 09145087 NLM ISO Abbreviation: J Cardiol Subsets: MEDLINE
    • Publication Information:
      Publication: Amsterdam : Elsevier
      Original Publication: Tokyo : Japanese College Of Cardiology
    • Subject Terms:
      Coronary Circulation*; Glucose/*metabolism ; Myocardial Infarction/*diagnostic imaging ; Myocardium/*metabolism; Adult ; Aged ; Deoxyglucose/analogs & derivatives ; Female ; Fluorine Radioisotopes ; Fluorodeoxyglucose F18 ; Heart/diagnostic imaging ; Humans ; Male ; Middle Aged ; Myocardial Infarction/physiopathology ; Nitrogen Radioisotopes ; Radiography ; Tomography, Emission-Computed
    • Abstract:
      Myocardial positron emission tomography (PET) using N-13-ammonia (NH3) and F-18-fluorodeoxyglucose (FDG) was performed in 16 patients with myocardial infarction to assess myocardial blood flow and glucose utilization. These PET data were also compared by left ventriculography. N-13-ammonia PET study was performed at rest and after supine ergometer exercise as a measure of myocardial blood flow, and the F-18-FDG PET study was performed at rest after more than five hours' fasting as a measure of glucose utilization. The N-13-ammonia PET study revealed hypoperfused regions in 15 of 16 patients (94%) corresponding to the infarct regions identified by electrocardiography and by cardiac catheterization. In 12 of 16 patients (75%) these hypoperfused regions expanded with exercise. FDG uptake was observed in the hypoperfused regions, especially in stress-induced ischemic ones. Increased uptake of FDG was more often observed in patients with mildly hypokinetic wall motion on left ventriculography. However, FDG PET studies demonstrated diffuse uptake of FDG in some of the akinetic and dyskinetic segments.
    • Accession Number:
      0 (Fluorine Radioisotopes)
      0 (Nitrogen Radioisotopes)
      0Z5B2CJX4D (Fluorodeoxyglucose F18)
      9G2MP84A8W (Deoxyglucose)
      IY9XDZ35W2 (Glucose)
    • Publication Date:
      Date Created: 19880301 Date Completed: 19890317 Latest Revision: 20161123
    • Publication Date:
      20240627
    • Accession Number:
      3265437