Atypical Topographical Organization of Global Form and Motion Processing in 5-Month-Old Infants at Risk for Autism.

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  • Additional Information
    • Source:
      Publisher: Springer Country of Publication: United States NLM ID: 7904301 Publication Model: Print Cited Medium: Internet ISSN: 1573-3432 (Electronic) Linking ISSN: 01623257 NLM ISO Abbreviation: J Autism Dev Disord Subsets: MEDLINE
    • Publication Information:
      Publication: <2006- >: New York, NY : Springer
      Original Publication: New York, Plenum Press.
    • Subject Terms:
      Autism Spectrum Disorder/*diagnosis ; Autism Spectrum Disorder/*physiopathology ; Electroencephalography/*methods ; Evoked Potentials, Visual/*physiology ; Motion Perception/*physiology ; Photic Stimulation/*methods; Female ; Humans ; Infant ; Male ; Risk Factors
    • Abstract:
      Research indicates that individuals with autism spectrum disorder (ASD) are superior at local processing while the integration of local features to global percepts is reduced. Here, we compared infants at familiar risk for ASD to typically developing infants in terms of global coherence processing at 5 months of age, using steady state visually evoked potentials (SSVEP). We found a different topographical organization for global form and motion processing in infants at risk (n = 50) than in controls (n = 23). In contrast, activation patterns for local visual change were strikingly similar between groups. Although preliminary, the results represent the first neurophysiological evidence supporting the view that basic atypicalities in perception may play a role in the developmental pathways leading to ASD.
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    • Grant Information:
      2015-03670 Riksbankens Jubileumsfond; 777394 Innovative Medicines Initiative
    • Contributed Indexing:
      Keywords: Autism; Developmental disorders; EEG; Global coherence; Infants; Motion
    • Publication Date:
      Date Created: 20200528 Date Completed: 20210413 Latest Revision: 20210413
    • Publication Date:
      20221213
    • Accession Number:
      PMC7810644
    • Accession Number:
      10.1007/s10803-020-04523-2
    • Accession Number:
      32458154