Robust organ size requires robust timing of initiation orchestrated by focused auxin and cytokinin signalling.

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  • Additional Information
    • Source:
      Publisher: Nature Publishing Group, a division of Macmillan Publishers Limited Country of Publication: England NLM ID: 101651677 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2055-0278 (Electronic) Linking ISSN: 20550278 NLM ISO Abbreviation: Nat Plants Subsets: MEDLINE
    • Publication Information:
      Original Publication: [London, UK] : Nature Publishing Group, a division of Macmillan Publishers Limited, [2015]-
    • Subject Terms:
      Arabidopsis/*growth & development ; Arabidopsis Proteins/*genetics ; Cytokinins/*metabolism ; DNA-Binding Proteins/*genetics ; Indoleacetic Acids/*metabolism ; Organogenesis, Plant/*genetics ; Signal Transduction/*genetics; Arabidopsis/genetics ; Arabidopsis/metabolism ; Arabidopsis Proteins/metabolism ; DNA-Binding Proteins/metabolism ; Flowers/genetics ; Flowers/growth & development
    • Abstract:
      Organ size and shape are precisely regulated to ensure proper function. The four sepals in each Arabidopsis thaliana flower must maintain the same size throughout their growth to continuously enclose and protect the developing bud. Here we show that DEVELOPMENT RELATED MYB-LIKE 1 (DRMY1) is required for both timing of organ initiation and proper growth, leading to robust sepal size in Arabidopsis. Within each drmy1 flower, the initiation of some sepals is variably delayed. Late-initiating sepals in drmy1 mutants remain smaller throughout development, resulting in variability in sepal size. DRMY1 focuses the spatiotemporal signalling patterns of the plant hormones auxin and cytokinin, which jointly control the timing of sepal initiation. Our findings demonstrate that timing of organ initiation, together with growth and maturation, contribute to robust organ size.
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    • Grant Information:
      R01 GM134037 United States GM NIGMS NIH HHS; S10 OD010693 United States OD NIH HHS
    • Accession Number:
      0 (AT1G58220 protein, Arabidopsis)
      0 (Arabidopsis Proteins)
      0 (Cytokinins)
      0 (DNA-Binding Proteins)
      0 (Indoleacetic Acids)
    • Publication Date:
      Date Created: 20200527 Date Completed: 20210303 Latest Revision: 20240329
    • Publication Date:
      20240329
    • Accession Number:
      PMC7299778
    • Accession Number:
      10.1038/s41477-020-0666-7
    • Accession Number:
      32451448