Surgical site infection prevention protocol for pediatric spinal deformity surgery: does it make a difference?

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  • Additional Information
    • Source:
      Publisher: Springer Nature Country of Publication: England NLM ID: 101603979 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2212-1358 (Electronic) Linking ISSN: 2212134X NLM ISO Abbreviation: Spine Deform Subsets: MEDLINE
    • Publication Information:
      Publication: 2020- : London : Springer Nature
      Original Publication: New York, N.Y. : Elsevier
    • Subject Terms:
      Antibiotic Prophylaxis/*methods ; Patient Care Bundles/*methods ; Scoliosis/*surgery ; Spinal Fusion/*adverse effects ; Surgical Wound Infection/*epidemiology ; Surgical Wound Infection/*prevention & control; Administration, Intranasal ; Adolescent ; Baths ; Child ; Chlorhexidine/analogs & derivatives ; Female ; Humans ; Incidence ; Male ; Methicillin-Resistant Staphylococcus aureus ; Mupirocin/administration & dosage ; Powders ; Spinal Fusion/methods ; Surgical Wound Infection/etiology ; Surgical Wound Infection/microbiology ; Vancomycin/administration & dosage
    • Abstract:
      Study Design: Retrospective.
      Objective: Can a standardized, hospital-wide care bundle decrease surgical site infection (SSI) rate in pediatric spinal deformity surgery? SSI is a major concern in pediatric spinal deformity surgery.
      Methods: We performed a retrospective review of our primary scoliosis surgeries between 1999 and 2017. In 2008, we implemented a standardized infection reduction bundle. Interventions included preoperative nares screening for methicillin-resistant staphylococcus aureus or methicillin-sensitive Staphylococcus aureus 2 weeks preoperatively, and treatment with intranasal mupirocin when positive, a bath or shower the night before surgery, a preoperative chlorohexidine scrub, timing of standardized antibiotic administration, standardized intraoperative re-dosing of antibiotics, limiting operating room traffic, and standardized postoperative wound care. In 2011, we added intrawound vancomycin powder at wound closure. Our inclusion criteria were patients 21 years of age or less with idiopathic, neuromuscular, syndromic, or congenital scoliosis who had a primary spinal fusion or a same day anterior and posterior spine fusion with segmental spinal instrumentation of six levels or more. We compared the incidence of early (within 90 days of surgery) and late (> 91 days) SSI during the first postoperative year.
      Results: There were 804 patients who met inclusion criteria: 404 in the non-bundle group (NBG) for cases prior to protocol change and 400 in the bundle group (BG) for cases after the protocol change. Postoperatively, there were 29 infections (7.2% of total cases) in the NBG: 9 early (2.2%) and 20 late (5.0%) while in the BG there were only 10 infection (2.5%): 6 early (1.5%) and 4 late (1.0%). The reduction in overall SSIs was statistically significant (p = 0.01). There was a trend toward decreased early infections in the BG, without reaching statistical significance (p = 0.14).
      Conclusion: Standardized care bundles appear effective in reducing the incidence of postoperative pediatric spine SSIs.
      Level of Evidence: Level III.
    • Contributed Indexing:
      Keywords: Antibiotics; Bundle; SSI; Scoliosis; Surgical site infection
    • Accession Number:
      0 (Powders)
      6Q205EH1VU (Vancomycin)
      D0GX863OA5 (Mupirocin)
      MOR84MUD8E (chlorhexidine gluconate)
      R4KO0DY52L (Chlorhexidine)
    • Publication Date:
      Date Created: 20200502 Date Completed: 20201118 Latest Revision: 20201118
    • Publication Date:
      20221213
    • Accession Number:
      10.1007/s43390-020-00120-6
    • Accession Number:
      32356280