The effects of dietary sodium butyrate supplementation on the growth performance, carcass traits and intestinal microbiota of growing-finishing pigs.

Publisher: Oxford University Press Country of Publication: England NLM ID: 9706280 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2672 (Electronic) Linking ISSN: 13645072 NLM ISO Abbreviation: J Appl Microbiol Subsets: MEDLINE

Publication: 2022- : Oxford : Oxford University Press
Original Publication: Oxford : Published for the Society for Applied Bacteriology by Blackwell Science, c1997-

Animal Nutritional Physiological Phenomena* ; Dietary Supplements* ; Gastrointestinal Microbiome*; Butyric Acid/*administration & dosage ; Swine/*growth & development; Animal Feed/analysis ; Animals ; Bacteria/classification ; Bacteria/isolation & purification ; Female ; Male ; Phenotype ; Weight Gain

Aim: This study was carried out to investigate the effects of dietary sodium butyrate supplementation on growth performance, carcass traits and intestinal of growing-finishing pigs.
Methods and Results: Thirty pigs (27·4 ± 0·4 kg) were randomly assigned to receive one of three diets: basal diet (negative control group), basal diet + 40 ppm zinc bacitracin (positive control group) and basal diet + 0·2% sodium butyrate (sodium butyrate group), respectively. The experiment lasted for 69 days, including 3 days for diet and housing condition adaptation. On day 70, five piglets from each diet group were slaughtered for collecting blood and tissue samples. When compared to the control group, final body weight, daily body weight gain and daily feed intake of pigs in the sodium butyrate group were increased (P < 0·05) and feed intake/body weight gain ratio was decreased (P < 0·05). Carcass weight of pigs in the sodium butyrate group was higher than that of pigs in the negative and positive groups (P < 0·05); backfat thickness of pigs in the positive group was higher than that of pigs in the negative group and sodium butyrate group (P < 0·001). When compared to the negative and positive groups, pigs fed diet supplemented with sodium butyrate showed a increased relative abundance of bacteroidetes in the caecum and a decreased relative abundance of fiemicutes and proteobacteria in the caecum (P < 0·05).
Conclusion: The results indicated that dietary sodium butyrate supplementation increased growth performance of growing-finishing pigs and improved the carcass traits and intestinal health.
Significance and Impact of the Study: Antibiotic-free feed has become an inevitable worldwide trend. This study showed that dietary sodium butyrate supplementation improved the growth performance and intestinal health of growing-finishing pigs. Thus, sodium butyrate can be applied in growing-finishing pig feed as an alternative of antibiotics.
(© 2020 The Society for Applied Microbiology.)

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XDJK2019B014 the Fundamental Research Funds for the Central Universities; cstc2018jcyjAX0025 the Natural Science Foundation Project of CQ CSTC; 31872370; 31772610 National Natural Science Foundation of China

Keywords: carcass trait; growth performance; intestinal health; pigs; sodium butyrate

107-92-6 (Butyric Acid)

Date Created: 20200213 Date Completed: 20200731 Latest Revision: 20200731

20240829

10.1111/jam.14612

32048746