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Health-related quality of life among patients with comorbid diabetes and kidney disease attending a codesigned integrated model of care: a longitudinal study.
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- Author(s): Zimbudzi E;Zimbudzi E;Zimbudzi E; Lo C; Lo C; Lo C; Ranasinha S; Ranasinha S; Teede H; Teede H; Teede H; Usherwood T; Usherwood T; Usherwood T; Polkinghorne KR; Polkinghorne KR; Polkinghorne KR; Fulcher G; Fulcher G; Fulcher G; Gallagher M; Gallagher M; Gallagher M; Jan S; Jan S; Jan S; Cass A; Cass A; Cass A; Walker R; Walker R; Russell G; Russell G; Johnson G; Johnson G; Kerr PG; Kerr PG; Kerr PG; Zoungas S; Zoungas S; Zoungas S
- Source:
BMJ open diabetes research & care [BMJ Open Diabetes Res Care] 2020 Jan; Vol. 8 (1).- Publication Type:
Journal Article; Research Support, Non-U.S. Gov't- Language:
English - Source:
- Additional Information
- Source: Publisher: Published by BMJ in partnership with the American Diabetes Association Country of Publication: England NLM ID: 101641391 Publication Model: Print Cited Medium: Internet ISSN: 2052-4897 (Electronic) Linking ISSN: 20524897 NLM ISO Abbreviation: BMJ Open Diabetes Res Care Subsets: MEDLINE
- Publication Information: Original Publication: London : Published by BMJ in partnership with the American Diabetes Association
- Subject Terms: Quality of Life*; Delivery of Health Care, Integrated/*organization & administration ; Diabetes Mellitus/*epidemiology ; Quality of Health Care/*standards ; Renal Insufficiency, Chronic/*epidemiology; Aged ; Australia/epidemiology ; Comorbidity ; Delivery of Health Care, Integrated/methods ; Female ; Follow-Up Studies ; Humans ; Incidence ; Longitudinal Studies ; Male ; Prognosis ; Surveys and Questionnaires
- Abstract: Objective: To evaluate the impact of an integrated diabetes and kidney disease model of care on health-related quality of life (HRQOL) of patients with comorbid diabetes and chronic kidney disease (CKD).
Research Design and Methods: A longitudinal study of adult patients (over 18 years) with comorbid diabetes and CKD (stage 3a or worse) who attended a new diabetes kidney disease service was conducted at a tertiary hospital. A questionnaire consisting of demographics, clinical data, and the Kidney Disease Quality of Life (KDQOL-36) was administered at baseline and after 12 months. Paired t-tests were used to compare baseline and 12-month scores. A subgroup analysis examined the effects by patient gender. Multiple regression analysis examined the factors associated with changes in scores.
Results: 179 patients, 36% of whom were female, with baseline mean±SD age of 65.9±11.3 years, were studied. Across all subscales, HRQOL did not significantly change over time (p value for all mean differences >0.05). However, on subgroup analysis, symptom problem list and physical composite summary scores increased among women (MD=9.0, 95% CI 1.25 to 16.67; p=0.02 and MD=4.5, 95% CI 0.57 to 8.42; p=0.03 respectively) and physical composite scores decreased among men (MD=-3.35, 95% CI -6.26 to -0.44; p=0.03).
Conclusion: The HRQOL of patients with comorbid diabetes and CKD attending a new codesigned, integrated diabetes and kidney disease model of care was maintained over 12 months. Given that HRQOL is known to deteriorate over time in this high-risk population, the impact of these findings on clinical outcomes warrants further investigation.
Competing Interests: Competing interests: None declared.
(© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.) - References: Support Care Cancer. 2017 Dec;25(12):3775-3783. (PMID: 28702685)
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Am J Kidney Dis. 2014 Oct;64(4):510-33. (PMID: 25257325) - Contributed Indexing: Keywords: chronic kidney disease; quality of Life; type 2 diabetes
- Publication Date: Date Created: 20200121 Date Completed: 20200929 Latest Revision: 20200929
- Publication Date: 20221213
- Accession Number: PMC6954749
- Accession Number: 10.1136/bmjdrc-2019-000842
- Accession Number: 31958294
- Source:
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