Disabilities in leprosy: an open, retrospective analyses of institutional records.

Publisher: Elsevier España, S.L Country of Publication: Spain NLM ID: 0067662 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1806-4841 (Electronic) Linking ISSN: 03650596 NLM ISO Abbreviation: An Bras Dermatol Subsets: MEDLINE

Publication: Barcelona, Spain : Elsevier España, S.L.
Original Publication: Rio De Janeiro : Sociedade Brasileira de Dermatologia

Disability Evaluation*; Leprosy/*pathology ; Leprosy/*physiopathology; Cross-Sectional Studies ; Disease Progression ; Face/abnormalities ; Female ; Follow-Up Studies ; Foot Deformities, Acquired/pathology ; Foot Deformities, Acquired/physiopathology ; Hand Deformities, Acquired/pathology ; Hand Deformities, Acquired/physiopathology ; Humans ; India ; Male ; Medical Records ; Peripheral Nerves/physiopathology ; Retrospective Studies ; Severity of Illness Index ; Time Factors

Background and Objectives: Leprosy remains a leading cause of peripheral neuropathy and disability in the world. Primary objective of the study was to determine the incidence of deformities present at a time of diagnosis and new deformities that patients develop over follow up period.
Material and Methods: An open, retrospective cohort study was performed at a tertiary medical center in western India. Recruitment phase of the study was of 2 years (2009-2010) followed by observation/follow up phase of 7 years till 31st December 2017. New patients with leprosy and released from treatment cases who presented with deformity as defined by WHO disability grade (1998) and subsequently developing new deformities during the follow up period of up to 7 years were included in the study.
Results: The study included 200 leprosy patients. Of the total 254 deformities, 168 (66.14%) deformities were noticed at the moment of diagnosis, 20 (7.87%) deformities occurred during the follow up phase. Of all patients, 21.25% had Grade 1 deformity and 6.31% had Grade 2 or more severe deformity. Deformities of hand were most common in 44.48%, followed by feet 39.76%, and face 15.74% respectively.
Limitation of Study: Mode of inclusion of patient was self-reporting during follow up phase so there is possible under reporting of the disabilities.
Conclusion: New deformities continue to develop in certain forms of leprosy even after release from treatment. Long-term & regular follow up of patients who have been released from treatment is required.
(Copyright © 2019 Sociedade Brasileira de Dermatologia. Published by Elsevier España, S.L.U. All rights reserved.)

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Keywords: Leprosy; Social stigma; Statistics on sequelae and disability

Date Created: 20200119 Date Completed: 20200330 Latest Revision: 20240727

20240727

PMC7058852

10.1016/j.abd.2019.07.001

31952993