Angiosarcoma arising in massive localized lymphedema.

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  • Author(s): Dyroff S;Dyroff S; Layfield LJ; Layfield LJ; Crim J; Crim J
  • Source:
    Skeletal radiology [Skeletal Radiol] 2020 May; Vol. 49 (5), pp. 815-818. Date of Electronic Publication: 2020 Jan 16.
  • Publication Type:
    Case Reports; Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Springer Verlag Country of Publication: Germany NLM ID: 7701953 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-2161 (Electronic) Linking ISSN: 03642348 NLM ISO Abbreviation: Skeletal Radiol Subsets: MEDLINE
    • Publication Information:
      Publication: Berlin : Springer Verlag
      Original Publication: Berlin, New York, Springer International.
    • Subject Terms:
      Hemangiosarcoma/*diagnostic imaging ; Lymphedema/*complications ; Magnetic Resonance Imaging/*methods ; Soft Tissue Neoplasms/*diagnostic imaging ; Tomography, X-Ray Computed/*methods; Aged ; Biopsy ; Diagnosis, Differential ; Female ; Hemangiosarcoma/complications ; Hemangiosarcoma/pathology ; Humans ; Soft Tissue Neoplasms/complications ; Soft Tissue Neoplasms/pathology ; Thigh/diagnostic imaging ; Thigh/pathology
    • Abstract:
      We report a case of a 70-year-old woman with a BMI of 58 who developed cellulitis refractory to treatment, within an area of massive localized lymphedema. Biopsy showed angiosarcoma. MRI showed multiple lobulated, low T1, high T2 masses within a background of prominent soft tissue septal stranding, dilated lymphatic channels, and skin thickening. CT also showed the mass well, within the background lymphedema. Massive localized lymphedema is increasing in prevalence due to the worsening obesity epidemic. Radiologists should be aware that the presence of a nodule within an area of massive localized lymphedema is suspicious for sarcoma.
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    • Contributed Indexing:
      Keywords: Adiposis dolorosa; Angiosarcoma; Lymphedema; Massive localized lymphedema; Stewart–Treves syndrome
    • Publication Date:
      Date Created: 20200118 Date Completed: 20210125 Latest Revision: 20210125
    • Publication Date:
      20221213
    • Accession Number:
      10.1007/s00256-020-03373-4
    • Accession Number:
      31950200