Spontaneous aortic thrombosis in neonates: a case report and review of literature.

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  • Additional Information
    • Source:
      Publisher: Cambridge University Press Country of Publication: England NLM ID: 9200019 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1467-1107 (Electronic) Linking ISSN: 10479511 NLM ISO Abbreviation: Cardiol Young Subsets: MEDLINE
    • Publication Information:
      Publication: <2005->: Cambridge : Cambridge University Press
      Original Publication: Chapel Hill, NC : World Publishers, c1991-
    • Subject Terms:
      Aorta, Thoracic/*pathology ; Aortic Diseases/*diagnosis ; Fibrinolytic Agents/*therapeutic use ; Thrombosis/*diagnosis; Aortic Diseases/drug therapy ; Diagnosis, Differential ; Humans ; Infant, Newborn ; Magnetic Resonance Imaging ; Male ; Thrombolytic Therapy ; Thrombosis/drug therapy
    • Abstract:
      Neonatal aortic thrombosis is a rare occurrence but can be life-threatening. Most aortic thrombosis in neonates is related to umbilical artery catheters. A case of a neonate with a spontaneous aortic thrombosis is described here along with a comprehensive review of the literature for cases of neonatal aortic thrombosis not related to any intravascular device or procedure. The aetiologies of these spontaneous thromboses and the relevance of hypercoagulable disorders are discussed. The cases were analysed for odds of death by treatment method adjusted for era. The reference treatment method was thrombolysis and anticoagulation. No other treatment modality had significantly lower odds than the reference. Surgery alone had higher odds for death than the reference, but this may be confounded by severity of case. The management recommendations for clinicians encountering neonates with spontaneous neonatal aortic thrombosis are discussed.
    • Contributed Indexing:
      Keywords: Spontaneous thrombosis; aortic thrombosis; clot; neonate
    • Accession Number:
      0 (Fibrinolytic Agents)
    • Publication Date:
      Date Created: 20200108 Date Completed: 20201130 Latest Revision: 20201130
    • Publication Date:
      20221213
    • Accession Number:
      10.1017/S1047951119003093
    • Accession Number:
      31907090