The Role of Deubiquitinases in Vascular Diseases.

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  • Author(s): Wang B;Wang B; Cai W; Cai W; Ai D; Ai D; Zhang X; Zhang X; Yao L; Yao L
  • Source:
    Journal of cardiovascular translational research [J Cardiovasc Transl Res] 2020 Apr; Vol. 13 (2), pp. 131-141. Date of Electronic Publication: 2019 Dec 10.
  • Publication Type:
    Journal Article; Research Support, Non-U.S. Gov't; Review
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Springer Country of Publication: United States NLM ID: 101468585 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1937-5395 (Electronic) Linking ISSN: 19375387 NLM ISO Abbreviation: J Cardiovasc Transl Res Subsets: MEDLINE
    • Publication Information:
      Original Publication: New York, NY : Springer
    • Subject Terms:
      Blood Vessels/*enzymology ; Deubiquitinating Enzymes/*metabolism ; Vascular Diseases/*enzymology; Animals ; Blood Vessels/pathology ; Blood Vessels/physiopathology ; Humans ; Lysine ; Signal Transduction ; Ubiquitination ; Vascular Diseases/pathology ; Vascular Diseases/physiopathology
    • Abstract:
      Deubiquitinases (DUBs) are a major component of the ubiquitin-proteasome system in eukaryotic cells; the system plays a crucial role in many biological processes, such as inflammation, oxidative stress, and cell apoptosis, which are important in vascular biology and pathology. DUBs have drawn significant attention in recent years, and their function is increasingly linked with vascular diseases. In this review, we summarize the indirect and direct evidence for the effects of DUBs on atherosclerosis, abdominal aortic aneurysm, angiogenesis, and hypertension, and point out pathways that could be pursued for investigating DUBs. Intervention in the function of DUBs in vascular diseases has potential therapeutic value.
    • References:
      Arterioscler Thromb Vasc Biol. 2017 Sep;37(9):1698-1709. (PMID: 28751569)
      J Biol Chem. 2008 Apr 4;283(14):8802-9. (PMID: 18222923)
      Curr Atheroscler Rep. 2008 Jun;10(3):216-23. (PMID: 18489849)
      Cell Mol Immunol. 2012 Mar;9(2):123-30. (PMID: 22343828)
      EMBO Rep. 2018 Oct;19(10):. (PMID: 30206189)
      Cell Mol Life Sci. 2011 Jan;68(1):15-26. (PMID: 20730552)
      Arterioscler Thromb Vasc Biol. 2009 Aug;29(8):1213-9. (PMID: 19443843)
      Circulation. 2003 Sep 2;108(9):1113-8. (PMID: 12885753)
      Am J Cardiovasc Dis. 2015 Mar 10;5(1):83-100. (PMID: 26064796)
      J Clin Invest. 1995 Jul;96(1):60-8. (PMID: 7542286)
      Mol Cell Biol. 2005 May;25(10):3886-95. (PMID: 15870263)
      Mediators Inflamm. 2013;2013:127170. (PMID: 23983401)
      J Biol Chem. 2007 Dec 28;282(52):37885-93. (PMID: 17967898)
      Proc Natl Acad Sci U S A. 2012 May 15;109(20):7865-70. (PMID: 22550173)
      Sci Signal. 2010 May 25;3(123):ra42. (PMID: 20501938)
      Nat Med. 2003 Jun;9(6):677-84. (PMID: 12778166)
      FEBS Lett. 2017 Feb;591(3):479-490. (PMID: 28094437)
      FASEB J. 2006 Jul;20(9):1418-30. (PMID: 16816117)
      Nature. 2011 Mar 31;471(7340):591-6. (PMID: 21455173)
      J Am Soc Nephrol. 2008 Nov;19(11):2170-80. (PMID: 18701608)
      Int J Oncol. 2017 May;50(5):1663-1670. (PMID: 28339037)
      Exp Cell Res. 2006 Sep 10;312(15):2897-907. (PMID: 16824518)
      Nature. 2013 Jun 20;498(7454):318-24. (PMID: 23708998)
      Blood. 2004 Oct 15;104(8):2376-84. (PMID: 15251990)
      Cell Death Discov. 2018 May 16;4:60. (PMID: 29796309)
      Circ Res. 2018 Jun 8;122(12):1722-1740. (PMID: 29880500)
      J Biol Chem. 2011 Dec 2;286(48):41692-700. (PMID: 21971051)
      Biochem Biophys Res Commun. 2018 May 15;499(3):702-710. (PMID: 29605299)
      Cell Death Dis. 2017 Jul 13;8(7):e2917. (PMID: 28703797)
      BMC Cancer. 2015 Nov 10;15:886. (PMID: 26555296)
      Science. 1995 Mar 10;267(5203):1449-56. (PMID: 7533326)
      Biorheology. 2009;46(1):21-30. (PMID: 19252225)
      Mol Cell Biol. 2007 Nov;27(21):7451-61. (PMID: 17709380)
      J Biol Chem. 2007 Jul 13;282(28):20207-12. (PMID: 17502380)
      Nat Med. 2018 Jan;24(1):84-94. (PMID: 29227477)
      Am J Pathol. 2008 Mar;172(3):818-29. (PMID: 18245814)
      J Cell Physiol. 2006 Aug;208(2):307-18. (PMID: 16646083)
      Cell. 2009 Jul 23;138(2):389-403. (PMID: 19615732)
      Cold Spring Harb Perspect Med. 2012 Aug 01;2(8):. (PMID: 22908190)
      Can J Physiol Pharmacol. 2017 May;95(5):481-491. (PMID: 28134560)
      Nature. 2003 Aug 14;424(6950):801-5. (PMID: 12917691)
      Biochemistry. 2012 Apr 3;51(13):2829-39. (PMID: 22439892)
      Mol Cell Biol. 1995 Mar;15(3):1265-73. (PMID: 7862120)
      Cell Signal. 2012 Nov;24(11):2123-31. (PMID: 22820500)
      Cardiovasc Res. 2010 Jan 15;85(2):291-302. (PMID: 19815565)
      J Exp Med. 1997 Apr 21;185(8):1511-6. (PMID: 9126933)
      Acta Pharmacol Sin. 2016 Jul;37(7):889-97. (PMID: 27063215)
      Cell. 2004 Jan 23;116(2):181-90. (PMID: 14744430)
      Nat Rev Mol Cell Biol. 2009 Aug;10(8):550-63. (PMID: 19626045)
      Mol Med Rep. 2017 May;15(5):2567-2573. (PMID: 28447728)
      Nature. 2014 Aug 7;512(7512):69-73. (PMID: 25043000)
      EMBO Rep. 2008 Jun;9(6):536-42. (PMID: 18516089)
      Blood. 2010 May 20;115(20):4130-7. (PMID: 20194890)
      Science. 2019 Apr 12;364(6436):188-193. (PMID: 30975888)
      Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18601-6. (PMID: 18006655)
      Biochem Biophys Res Commun. 2018 Jan 1;495(1):1567-1572. (PMID: 29128359)
      Am J Physiol Cell Physiol. 2013 Nov 15;305(10):C1021-32. (PMID: 24048733)
      Mol Cell. 2013 Jan 24;49(2):331-8. (PMID: 23246432)
      J Biol Chem. 2011 Mar 25;286(12):10457-65. (PMID: 21278249)
      Cell Biochem Biophys. 2011 Jun;60(1-2):21-38. (PMID: 21480003)
      Cell. 2005 Dec 2;123(5):773-86. (PMID: 16325574)
      Am J Physiol Cell Physiol. 2011 Sep;301(3):C695-704. (PMID: 21653897)
      Biochem Biophys Res Commun. 2009 Apr 24;382(1):145-8. (PMID: 19268428)
      J Am Soc Nephrol. 2006 Jul;17(7):1807-19. (PMID: 16738015)
      Curr Opin Pharmacol. 2014 Apr;15:33-46. (PMID: 24721652)
      Int J Mol Sci. 2012;13(9):11804-31. (PMID: 23109884)
      Circ Res. 2016 Feb 19;118(4):653-67. (PMID: 26892964)
      Thromb Haemost. 2013 Jul;110(1):141-52. (PMID: 23636414)
      Nature. 2010 Apr 29;464(7293):1357-61. (PMID: 20428172)
      Arch Med Res. 2017 Jan;48(1):12-26. (PMID: 28577865)
      EMBO J. 2009 Jun 17;28(12):1684-96. (PMID: 19424180)
      Nature. 2000 Sep 14;407(6801):233-41. (PMID: 11001066)
      Front Plant Sci. 2011 Nov 22;2:87. (PMID: 22645554)
      Cell. 2011 Apr 29;145(3):341-55. (PMID: 21529710)
      Arterioscler Thromb Vasc Biol. 2007 Oct;27(10):2184-90. (PMID: 17690318)
      J Cardiovasc Transl Res. 2018 Oct;11(5):429-437. (PMID: 30276617)
      Int J Oncol. 2018 Aug;53(2):895-903. (PMID: 29901102)
      J Nat Sci Biol Med. 2013 Jan;4(1):238-42. (PMID: 23633873)
      J Cardiovasc Transl Res. 2019 Feb;12(1):1-2. (PMID: 30617761)
      Nat Commun. 2018 Oct 12;9(1):4225. (PMID: 30315153)
      Biochem Biophys Res Commun. 2017 Jan 29;483(1):69-74. (PMID: 28063927)
      Arterioscler Thromb Vasc Biol. 2018 Oct;38(10):2295-2305. (PMID: 30354204)
      Biochemistry. 2012 Nov 13;51(45):9112-23. (PMID: 23116119)
      Compr Physiol. 2012 Oct;2(4):2393-442. (PMID: 23720252)
      J Exp Med. 2010 Dec 20;207(13):2959-73. (PMID: 21115689)
      Prog Mol Biol Transl Sci. 2012;109:295-346. (PMID: 22727426)
      J Biol Chem. 2016 Apr 1;291(14):7450-64. (PMID: 26839314)
      J Am Soc Nephrol. 2001 Mar;12(3):456-63. (PMID: 11181793)
      N Engl J Med. 2005 Apr 21;352(16):1685-95. (PMID: 15843671)
      Arterioscler Thromb Vasc Biol. 2017 Nov;37(11):2087-2101. (PMID: 28882872)
      Mol Cell. 2011 Oct 7;44(1):147-59. (PMID: 21981925)
      J Cardiovasc Transl Res. 2019 Jun;12(3):165-170. (PMID: 30535628)
      Blood. 2014 Jan 30;123(5):625-31. (PMID: 24300855)
      Science. 2010 May 21;328(5981):1025-9. (PMID: 20395473)
      Arterioscler Thromb Vasc Biol. 2011 Nov;31(11):2391-6. (PMID: 21868702)
      Crit Rev Eukaryot Gene Expr. 2010;20(2):87-103. (PMID: 21133840)
      Science. 2007 Jan 12;315(5809):201-5. (PMID: 17218518)
      Nat Commun. 2019 Apr 23;10(1):1834. (PMID: 31015422)
      Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7458-63. (PMID: 10861012)
      J Biol Chem. 2013 Feb 22;288(8):5389-97. (PMID: 23297398)
      Trends Immunol. 2009 Aug;30(8):383-91. (PMID: 19643665)
      Am J Physiol Cell Physiol. 2002 May;282(5):C947-70. (PMID: 11940508)
      J Biol Chem. 2010 Jul 30;285(31):23527-31. (PMID: 20460373)
      Nature. 2000 Sep 14;407(6801):249-57. (PMID: 11001068)
      Development. 2019 Feb 22;146(4):. (PMID: 30718289)
      Antioxid Redox Signal. 2014 Mar 20;20(9):1382-95. (PMID: 24063548)
      Am J Kidney Dis. 2019 Jul;74(1):120-131. (PMID: 30898362)
      Circ J. 2016 Oct 25;80(11):2259-2268. (PMID: 27725526)
      Nat Rev Mol Cell Biol. 2019 Jun;20(6):338-352. (PMID: 30733604)
      Am J Physiol Renal Physiol. 2013 Jul 1;305(1):F21-30. (PMID: 23552861)
    • Contributed Indexing:
      Keywords: Abdominal Aortic Aneurysm; Angiogenesis; Atherosclerosis; Deubiquitinases; Hypertension
    • Accession Number:
      EC 3.4.19.12 (Deubiquitinating Enzymes)
      K3Z4F929H6 (Lysine)
    • Publication Date:
      Date Created: 20191212 Date Completed: 20201007 Latest Revision: 20201007
    • Publication Date:
      20231215
    • Accession Number:
      10.1007/s12265-019-09909-x
    • Accession Number:
      31823221