The value of anti-rods and rings antibodies in Western China population: A retrospective study.

Publisher: Blackwell Scientific Publications Country of Publication: England NLM ID: 0323767 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-3083 (Electronic) Linking ISSN: 03009475 NLM ISO Abbreviation: Scand J Immunol Subsets: MEDLINE

Publication: Oxford : Blackwell Scientific Publications
Original Publication: Oslo, Universitetsforlaget.

Antibodies, Antinuclear/*immunology ; Autoantibodies/*immunology; Adult ; Aged ; Antibodies, Antinuclear/blood ; Asian People ; Autoantibodies/blood ; Autoimmune Diseases/blood ; Autoimmune Diseases/immunology ; China ; Female ; Fluorescent Antibody Technique ; Humans ; Male ; Middle Aged ; Population Surveillance ; Retrospective Studies ; Virus Diseases/blood ; Virus Diseases/immunology

The study aimed to retrospectively investigate the clinical significance of anti-rods and rings (anti-RR) antibodies in antinuclear antibodies (ANAs) test samples of western China. Between January 2016 and November 2018, the laboratory data and clinical details of patients with positive anti-RR antibodies were collected and analysed. The results showed that total of 197 227 patients tested, 109 453 patients presented with positive ANAs (55.50%), but only 107 patients with positive anti-RR antibodies (0.10%), including 51 females and 56 males. Diagnose were established in 51 of 107 patients: 25 were hepatopathy (HCV 8/25, HBV 12/25); 13 were autoimmune diseases (AID); and 7 were renal insufficiency; 6 were chronic obstructive pulmonary disease (COPD). We make the conclusions that anti-RR antibodies have a low prevalence, and there is no gender difference. Anti-RR antibodies exist other diseases besides hepatitis C, such as HBV, some autoimmune diseases, renal insufficiency and COPD, which we need further investigation.
(© 2019 The Scandinavian Foundation for Immunology.)

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ZYJC18042 Sichuan University; Z2018C03 Sichuan University

Keywords: anti-rods and rings antibodies; antinuclear antibodies; hepatitis B; hepatitis C; hepatopathy

0 (Antibodies, Antinuclear)
0 (Autoantibodies)

Date Created: 20191113 Date Completed: 20200226 Latest Revision: 20221207

20231215

10.1111/sji.12848

31713248