Inter-breed diversity and temporal dynamics of the faecal microbiota in healthy horses.

Publisher: Blackwell Country of Publication: Germany NLM ID: 100955807 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1439-0388 (Electronic) Linking ISSN: 09312668 NLM ISO Abbreviation: J Anim Breed Genet Subsets: MEDLINE

Publication: 1994- : Berlin : Blackwell
Original Publication: Hamburg : P. Parey, c1985-

Genetic Variation*; Feces/*microbiology ; Horses/*microbiology ; Microbiota/*genetics; Animals ; Female ; Horses/genetics ; Male ; Pedigree ; RNA, Ribosomal, 16S/genetics

Understanding gut microbiota similarities and differences across breeds in horses has the potential to advance approaches aimed at personalized microbial modifications, particularly those involved in improving sport athletic performance. Here, we explore whether faecal microbiota composition based on faecal 16S ribosomal RNA gene sequencing varies across six different sport breeds at two time points 8 months apart within a cohort of 189 healthy horses cared for under similar conditions. Lusitano horses presented the smallest and Hanoverians the greatest bacterial diversity. We found subtle but significant differences in β-diversity between Lusitano, Anglo Arabian and the central European breeds, and we reproduced these results across the two time points. Repeat sampling of subjects showed community to be temporally more stable in Lusitano and Anglo Arabian breeds. Additionally, we found that 27 genera significantly varied in abundance across breeds. Overall, 33% of these taxa overlapped with previously identified taxa that were associated with genetic variation in humans or other species. However, a non-significant correlation was observed between microbial composition and the host pedigree-based kinship. Despite a notable variation in the diversity and composition of the faecal microbiota, breed exerted limited effects on the equine faecal microbiota.
(© 2019 Blackwell Verlag GmbH.)

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Institut Français du Cheval et de l'Equitation; Fonds Eperon

Keywords: breed; discipline; faecal microbiota; horse

0 (RNA, Ribosomal, 16S)

Date Created: 20190917 Date Completed: 20200601 Latest Revision: 20200601

20250114

10.1111/jbg.12441

31523867