The influence of the levonorgestrel-releasing intrauterine system position on bleeding patterns in reproductive age women.

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  • Additional Information
    • Source:
      Publisher: Wiley Country of Publication: United States NLM ID: 0210174 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-3479 (Electronic) Linking ISSN: 00207292 NLM ISO Abbreviation: Int J Gynaecol Obstet Subsets: MEDLINE
    • Publication Information:
      Publication: 2017- : Malden, MA : Wiley
      Original Publication: [New York, NY] Hoeber Medical Division, Harper & Row, [c1969-
    • Subject Terms:
      Contraceptive Agents, Female/*pharmacology ; Intrauterine Devices, Medicated/*adverse effects ; Levonorgestrel/*pharmacology ; Menstruation Disturbances/*chemically induced; Adult ; Case-Control Studies ; Contraceptive Agents, Female/adverse effects ; Female ; Humans ; Levonorgestrel/adverse effects ; Prospective Studies ; Young Adult
    • Abstract:
      Objective: To determine whether users of the non-fundal levonorgestrel-releasing intrauterine system (LNG-IUS) present with unfavorable bleeding patterns more frequently than fundal LNG-IUS users.
      Methods: A prospective cohort was conducted from June, 2016 to January, 2018 involving women aged 18-45 years who wished to use the LNG-IUS as contraception and had no contraindications, endometrial polyps, submucosal myomas, irregular menstrual cycle, or anticoagulant use. Two study groups comprised women using fundal insertion and non-fundal insertion LNG-IUS. Bleeding was evaluated using a diary and pictogram chart.
      Results: Of the 92 women who participated in the study, those with non-fundal LNG-IUS insertion sustained bleeding at rates greater than 83% (31) in the first 3 months of use, and 58% (14) at 6 months, versus 51% (22) at 3 months and 33% (19) at 6 months in those with fundal insertion (P=0.002 at 3 months; P=0.037 at 6 months). Blood loss in the non-fundal LNG-IUS group was higher than in the fundal LNG-IUS group according to pictograms drawn by participants.
      Conclusion: Women with non-fundal LNG-IUS placement had a higher frequency of sustained bleeding and blood loss volume according to self-reported charts than those with fundal LNG-IUS placement.
      (© 2019 International Federation of Gynecology and Obstetrics.)
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    • Grant Information:
      Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo a Pesquisa do Estado da Bahia (FAPESB); International Contraceptive Access (ICA)
    • Contributed Indexing:
      Keywords: Bleeding; Contraception; Counseling; Intrauterine devices; Levonorgestrel-releasing IUS (intrauterine system); Long-acting reversible contraception; Position; Ultrasonography
    • Accession Number:
      0 (Contraceptive Agents, Female)
      5W7SIA7YZW (Levonorgestrel)
    • Publication Date:
      Date Created: 20190907 Date Completed: 20200121 Latest Revision: 20200121
    • Publication Date:
      20231215
    • Accession Number:
      10.1002/ijgo.12962
    • Accession Number:
      31489621