Ovarian Weight, Follicle Count and Retrieved Oocyte Characteristics in West African Dwarf Goat Does Experimentally Infected with Trypanosoma brucei.

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  • Author(s): Leigh OO;Leigh OO
  • Source:
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria [Niger J Physiol Sci] 2019 Jun 30; Vol. 34 (1), pp. 49-53. Date of Electronic Publication: 2019 Jun 30.
  • Publication Type:
    Journal Article
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Physiological Society of Nigeria Country of Publication: Nigeria NLM ID: 8811109 Publication Model: Electronic Cited Medium: Internet ISSN: 0794-859X (Print) Linking ISSN: 0794859X NLM ISO Abbreviation: Niger J Physiol Sci Subsets: MEDLINE
    • Publication Information:
      Original Publication: Benin City, Nigeria : Physiological Society of Nigeria
    • Subject Terms:
      Trypanosoma brucei brucei*; Oocyte Retrieval/*methods ; Oocytes/*pathology ; Ovarian Follicle/*pathology ; Trypanosomiasis, African/*pathology; Animals ; Female ; Goats ; Nigeria ; Organ Size ; Ovary/pathology ; Pregnancy
    • Abstract:
      Trypanosomosis has been described as the single largest disease entity limiting livestock development in sub-Saharan Africa. The effects on ovarian weight, follicle count and retrieved oocyte characteristics in ten West African dwarf goat does (control=5, infected=5) experimentally infected with Trypanosoma brucei were investigated. The does were fed with elephant grass and supplement (15.23% CP) daily. Infected does received 4.8x105 T. brucei intravenously and thereafter, all does were synchronized using Lutalyse®. The results showed that the differences between control and infected does for ovarian weight (0.68±0.56 g and 0.40±0.09 g) and follicle count (10.50±1.25 and 2.50±1.22),  respectively were significant (P<0.05). The difference in retrieved-oocytes-count between control (30, 57.7%) and infected (22, 42.3%)  does was not significant (P>0.05). The differences in proportion between control and infected does for well-formed-oocytes (90.5% and 9.5%), completely-denuded-oocytes (30.8% and 69.2%) and proportion per group of oocytes with substantial-investment-of-cumulus (63.3% and 9.1%), respectively were significant (P<0.05). The difference in extensively-denuded-oocytes between control (38.9%) and infected (61.1%) does was not significant (P>0.05). These findings suggest that experimental Trypanosoma brucei infection caused reduction in ovarian weight and follicle count, number of oocytes as well as proportion of well-formed oocytes that are capable of supporting embryonic development.
    • Publication Date:
      Date Created: 20190827 Date Completed: 20200213 Latest Revision: 20200213
    • Publication Date:
      20250114
    • Accession Number:
      31449271