Malignant melanoma arising from an end ileostomy.

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  • Additional Information
    • Source:
      Publisher: BMJ Pub. Group Country of Publication: England NLM ID: 101526291 Publication Model: Electronic Cited Medium: Internet ISSN: 1757-790X (Electronic) Linking ISSN: 1757790X NLM ISO Abbreviation: BMJ Case Rep Subsets: MEDLINE
    • Publication Information:
      Original Publication: London : BMJ Pub. Group
    • Subject Terms:
      Colitis, Ulcerative/*surgery ; Ileal Neoplasms/*etiology ; Ileostomy/*adverse effects ; Melanoma/*etiology ; Postoperative Complications/*etiology; Aged ; Humans ; Male
    • Abstract:
      A 65-year-old woman with a history of proctocolectomy and end ileostomy for ulcerative colitis was referred to our clinic with a slowly growing mass around her ileostomy. She did not report any systemic symptoms. On examination, an exophytic mass was observed around her ileostomy and hard lymph nodes palpated in her groins bilaterally. Punch biopsy of the lesion established a diagnosis of invasive melanoma. Positron emission tomography revealed regional metastatic lymphadenopathy in the right axilla and both groins. There was no evidence of distant metastatic disease. The patient then underwent wide local excision of her ileostomy with bowel resection and ileostomy re-siting, bilateral complete ilioinguinal lymphadenectomy and a right Level III axillary dissection. She is doing well postoperatively and receiving adjuvant systemic therapy with BRAF and MEK inhibitors, now 17 months later with no signs of recurrent disease.
      Competing Interests: Competing interests: None declared.
      (© BMJ Publishing Group Limited 2019. No commercial re-use. See rights and permissions. Published by BMJ.)
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    • Contributed Indexing:
      Keywords: dermatology; oncology; skin cancer; surgical oncology
    • Publication Date:
      Date Created: 20190803 Date Completed: 20200130 Latest Revision: 20210802
    • Publication Date:
      20250114
    • Accession Number:
      PMC6677946
    • Accession Number:
      10.1136/bcr-2019-230265
    • Accession Number:
      31371335