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Carbohydrates in Human Milk and Body Composition of Term Infants during the First 12 Months of Lactation.
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- Additional Information
- Source:
Publisher: MDPI Publishing Country of Publication: Switzerland NLM ID: 101521595 Publication Model: Electronic Cited Medium: Internet ISSN: 2072-6643 (Electronic) Linking ISSN: 20726643 NLM ISO Abbreviation: Nutrients Subsets: MEDLINE
- Publication Information:
Original Publication: Basel, Switzerland : MDPI Publishing
- Subject Terms:
- Abstract:
Human milk (HM) carbohydrates may affect infant appetite regulation, breastfeeding patterns, and body composition (BC). We investigated relationships between concentrations/calculated daily intakes (CDI) of HM carbohydrates in first year postpartum and maternal/term infant BC, as well as breastfeeding parameters. BC of dyads ( n = 20) was determined at 2, 5, 9, and/or 12 months postpartum using ultrasound skinfolds (infants) and bioelectrical impedance spectroscopy (infants/mothers). Breastfeeding frequency, 24-h milk intake and total carbohydrates (TCH) and lactose were measured to calculate HM oligosaccharides (HMO) concentration and CDI of carbohydrates. Statistical analysis used linear regression/mixed effects models; results were adjusted for multiple comparisons. Higher TCH concentrations were associated with greater infant length, weight, fat-free mass (FFM), and FFM index (FFMI), and decreased fat mass (FM), FM index (FMI), %FM and FM/FFM ratio. Higher HMO concentrations were associated with greater infant FFM and FFMI, and decreased FMI, %FM, and FM/FFM ratio. Higher TCH CDI were associated with greater FM, FMI, %FM, and FM/FFM ratio, and decreased infant FFMI. Higher lactose CDI were associated with greater FM, FMI, %FM, and FM/FFM, ratio and decreased FFMI. Concentrations and intakes of HM carbohydrates differentially influence development of infant BC in the first 12 months postpartum, and may potentially influence risk of later obesity via modulation of BC.
- References:
Am J Physiol Regul Integr Comp Physiol. 2000 Jul;279(1):R1-8. (PMID: 10896857)
Pediatrics. 2000 Dec;106(6):1355-66. (PMID: 11099589)
Glycobiology. 2001 May;11(5):365-72. (PMID: 11425797)
Int J Obes Relat Metab Disord. 2002 Jul;26(7):947-52. (PMID: 12080448)
Br J Nutr. 2002 Jul;88(1):29-37. (PMID: 12117425)
Pediatrics. 2006 Mar;117(3):e387-95. (PMID: 16510619)
J Agric Food Chem. 2006 Oct 4;54(20):7471-80. (PMID: 17002410)
Proc Nutr Soc. 2007 Aug;66(3):423-34. (PMID: 17637095)
J Paediatr Child Health. 2009 Apr;45(4):174-80. (PMID: 19426375)
Am J Clin Nutr. 1991 Feb;53(2):457-65. (PMID: 1989413)
Am J Clin Nutr. 1990 Dec;52(6):953-9. (PMID: 2239792)
Am J Hum Biol. 2012 Jul-Aug;24(4):533-40. (PMID: 22434662)
Glycobiology. 2012 Sep;22(9):1147-62. (PMID: 22513036)
Pediatr Obes. 2012 Aug;7(4):304-12. (PMID: 22577092)
J Hum Lact. 2013 Feb;29(1):81-9. (PMID: 22797414)
PLoS One. 2013;8(1):e53876. (PMID: 23326523)
J Hum Lact. 2013 May;29(2):196-204. (PMID: 23422498)
Carbohydr Polym. 2013 Sep 12;97(2):253-61. (PMID: 23911443)
J Pediatr Gastroenterol Nutr. 1990 Aug;11(2):229-39. (PMID: 2395063)
Am J Clin Nutr. 2013 Oct;98(4):1084-102. (PMID: 23966427)
Glycobiology. 2013 Nov;23(11):1281-92. (PMID: 24013960)
Pediatrics. 2014 Sep;134 Suppl 1:S29-35. (PMID: 25183752)
Ann Nutr Metab. 2014;64(3-4):187-96. (PMID: 25300259)
Nutrients. 2015 Mar 31;7(4):2237-60. (PMID: 25835047)
J Pediatr Gastroenterol Nutr. 1989 Nov;9(4):488-96. (PMID: 2621526)
Early Hum Dev. 2015 Nov;91(11):619-22. (PMID: 26375354)
Crit Rev Clin Lab Sci. 2016;53(1):52-67. (PMID: 26376619)
Am J Clin Nutr. 2015 Dec;102(6):1381-8. (PMID: 26511224)
Acta Paediatr. 2016 Jun;105(6):641-7. (PMID: 26865238)
Lancet. 2016 Jan 30;387(10017):475-90. (PMID: 26869575)
Nutrients. 2016 May 11;8(5):. (PMID: 27187450)
Pediatr Res. 2017 Mar;81(3):423-433. (PMID: 27828939)
Nutrients. 2016 Dec 28;9(1):null. (PMID: 28036041)
J Pediatr Gastroenterol Nutr. 2017 Apr;64(4):624-631. (PMID: 28107288)
Matern Child Health J. 2017 Jun;21(6):1367-1376. (PMID: 28138825)
PLoS One. 2017 Feb 9;12(2):e0171814. (PMID: 28182762)
Nutrients. 2017 Feb 16;9(2):null. (PMID: 28212335)
Nutrients. 2017 Mar 09;9(3):null. (PMID: 28282925)
Am J Clin Nutr. 2017 May;105(5):1086-1100. (PMID: 28356278)
Clin Nutr. 2018 Dec;37(6 Pt A):2284-2287. (PMID: 29056283)
Nutrients. 2018 Jan 05;10(1):null. (PMID: 29303992)
Nutrients. 2018 Aug 20;10(8):null. (PMID: 30127292)
Nutrients. 2018 Sep 04;10(9):null. (PMID: 30181524)
Nutrients. 2018 Sep 19;10(9):null. (PMID: 30235880)
J Nutr. 2018 Nov 1;148(11):1733-1742. (PMID: 30247646)
Am J Physiol Endocrinol Metab. 2019 Mar 1;316(3):E347-E357. (PMID: 30422706)
J Pediatr Gastroenterol Nutr. 1987 Sep-Oct;6(5):758-63. (PMID: 3694369)
Pediatrics. 1993 Mar;91(3):637-41. (PMID: 8441573)
- Grant Information:
unrestricted research grant Medela AG; Australian Postgraduate Award The University of Western Australia; Margaret Lomann-Hall Scholarship from the School of Human Sciences The University of Western Australia
- Contributed Indexing:
Keywords: body composition; breastfeeding frequency; daily intake; human milk carbohydrates; infant; lactation; lactose; milk intake; oligosaccharides
- Accession Number:
0 (Dietary Carbohydrates)
- Publication Date:
Date Created: 20190703 Date Completed: 20200129 Latest Revision: 20200225
- Publication Date:
20240829
- Accession Number:
PMC6683013
- Accession Number:
10.3390/nu11071472
- Accession Number:
31261649
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