Locus Minoris Resistentiae in Coccidioidomycosis: A Case Series.

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  • Additional Information
    • Source:
      Publisher: Sage on behalf of: American Federation for Medical Research Country of Publication: United States NLM ID: 101624758 Publication Model: Print Cited Medium: Internet ISSN: 2324-7096 (Electronic) Linking ISSN: 23247096 NLM ISO Abbreviation: J Investig Med High Impact Case Rep Subsets: MEDLINE
    • Publication Information:
      Original Publication: [Thousand Oaks, CA] : Sage on behalf of: American Federation for Medical Research
    • Subject Terms:
      Elbow Injuries*; Coccidioides/*isolation & purification ; Coccidioidomycosis/*diagnosis ; Dermatomycoses/*microbiology ; Lung Diseases, Fungal/*diagnostic imaging ; Tibial Meniscus Injuries/*complications; Adolescent ; Adult ; Humans ; Male ; Osteomyelitis/diagnostic imaging ; Tibial Meniscus Injuries/diagnostic imaging ; Tomography, X-Ray Computed ; X-Rays
    • Abstract:
      Locus minoris resistentiae refers to decreased resistance in any internal organ or external body region, leaving it more vulnerable to disease processes than other regions. These changes, either congenital or acquired, alter the defense capacity. The concept of locus minoris resistentiae is widely accepted in the medical field and presents itself across specialties. Antecedent trauma is a known risk factor for hematogenous dissemination of infection; this also applies to coccidioidal species. In this article, we describe 2 patients who suffered from pulmonary coccidioidomycosis with subsequent trauma resulting in osseous dissemination to the site of injury.
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    • Contributed Indexing:
      Keywords: San Joaquin fever; coccidioidomycosis; locus minoris resistentiae; valley fever
    • Publication Date:
      Date Created: 20190622 Date Completed: 20200519 Latest Revision: 20221207
    • Publication Date:
      20240829
    • Accession Number:
      PMC6589960
    • Accession Number:
      10.1177/2324709619858110
    • Accession Number:
      31220927