Organophosphorus Compounds Poisoning in a Neonate: A Case Report.

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  • Additional Information
    • Source:
      Publisher: Mymensingh Medical College Country of Publication: Bangladesh NLM ID: 9601799 Publication Model: Print Cited Medium: Internet ISSN: 2408-8757 (Electronic) Linking ISSN: 10224742 NLM ISO Abbreviation: Mymensingh Med J Subsets: MEDLINE
    • Publication Information:
      Original Publication: Mymensingh, Bangladesh : Mymensingh Medical College,
    • Subject Terms:
      Antidotes/*administration & dosage ; Atropine/*administration & dosage ; Insecticides/*poisoning ; Organophosphate Poisoning/*drug therapy ; Organophosphorus Compounds/*toxicity ; Pralidoxime Compounds/*administration & dosage; Antidotes/therapeutic use ; Atropine/therapeutic use ; Humans ; Infant, Newborn ; Male ; Organophosphorus Compounds/adverse effects ; Pralidoxime Compounds/therapeutic use ; Treatment Outcome
    • Abstract:
      Organophosphorus compounds (OPC) are widely used insecticides. Such poisoning is very rare in neonate. A 23 days old infant was admitted with severe respiratory distress, excessive secretion from nose and mouth, bluish discoloration of extremities and poor feeding for 4 hours. He was pale, cyanosed and lethargic with gasping respiration. Frothing was coming through mouth and nose. There was watering of eyes, pupils were pin pointed and light reflex was sluggish. The baby was hypothermic, hypotonic with altered sensorium. Capillary refill time was <3 sec. The neonate was gasping; there was crepitation over lung fields. Precordium and abdomen was normal. An odor of OPC was smelt on clothing and secretions of the infant. The baby was wrapped with a cloth that was ware during pesticide spraying in the field. In addition to general measures, decontamination of skin and clothing and gastric lavage was done. Empirical antibiotic, injection atropine and pralidoxime were given. Patient showed clinical improvement with disappearance of cholinergic signs. The baby was discharged on 7th day of admission after full recovery.
    • Accession Number:
      0 (Antidotes)
      0 (Insecticides)
      0 (Organophosphorus Compounds)
      0 (Pralidoxime Compounds)
      7C0697DR9I (Atropine)
      P7MU9UTP52 (pralidoxime)
    • Publication Date:
      Date Created: 20190516 Date Completed: 20190905 Latest Revision: 20190906
    • Publication Date:
      20231215
    • Accession Number:
      31086169