Conservative treatment of rectosigmoid endometriosis: A prospective study.

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  • Additional Information
    • Source:
      Publisher: Wiley Country of Publication: United States NLM ID: 0370343 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0412 (Electronic) Linking ISSN: 00016349 NLM ISO Abbreviation: Acta Obstet Gynecol Scand Subsets: MEDLINE
    • Publication Information:
      Publication: 2011- : Malden, MA : Wiley
      Original Publication: Copenhagen : Munksgaard
    • Subject Terms:
      Conservative Treatment* ; Intrauterine Devices, Medicated*; Contraceptives, Oral/*therapeutic use ; Endometriosis/*drug therapy ; Levonorgestrel/*therapeutic use ; Progestins/*therapeutic use ; Rectal Diseases/*drug therapy ; Sigmoid Diseases/*drug therapy; Administration, Oral ; Adult ; Denmark ; Endometriosis/diagnostic imaging ; Female ; Humans ; Pelvic Pain/drug therapy ; Prospective Studies ; Quality of Life ; Rectal Diseases/diagnostic imaging ; Sigmoid Diseases/diagnostic imaging ; Surveys and Questionnaires
    • Abstract:
      Introduction: Deep infiltrating endometriosis is a common cause of pelvic pain. However, some patients have limited problems that may be controlled by medical treatment, so avoiding the potentially severe complications of major surgery. This approach requires detailed knowledge on quality of life and clinical symptoms over time. The aim of the study was to monitor these parameters in patients with rectosigmoid endometriosis treated with oral contraceptives, oral gestagens, and/or the levonorgestrel-releasing intrauterine device. Moreover, nodule size measurements performed with transvaginal sonography were correlated to severity of symptoms.
      Material and Methods: Conservatively treated patients on oral contraceptives, oral gestagens, or the levonorgestrel-releasing intrauterine device underwent transvaginal sonography and answered a self-administered questionnaire regarding clinical symptoms and quality of life (Short Form 36 and Endometriosis Health Profile 30) at baseline, and 6 and 12 months later.
      Results: Eighty women completed the follow up. Scores of quality of life were comparable to normative data for Danish women of similar age and did not change with time. No association between change in size of the rectosigmoid nodule and change in symptoms was seen.
      Conclusions: This study supports that simple treatment with oral contraceptives, oral gestagens, or the levonorgestrel-releasing intrauterine device represents a viable therapeutic approach to rectosigmoid Deep infiltrating endometriosis, provided that proper selection of patients in need of surgery exists.
      (© 2019 Nordic Federation of Societies of Obstetrics and Gynecology (NFOG). Published by John Wiley & Sons Ltd.)
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    • Grant Information:
      International Knud og Edith Eriksens Mindefond; International Aarhus Universitet; International The Danish Endometriosis Society
    • Contributed Indexing:
      Keywords: bowel endometriosis; deep infiltrating endometriosis; dysmenorrhea; endometriosis; medical therapy; oral contraceptives; pelvic pain; progestins
    • Accession Number:
      0 (Contraceptives, Oral)
      0 (Progestins)
      5W7SIA7YZW (Levonorgestrel)
    • Publication Date:
      Date Created: 20190411 Date Completed: 20200318 Latest Revision: 20200318
    • Publication Date:
      20221213
    • Accession Number:
      10.1111/aogs.13619
    • Accession Number:
      30970147