[Effect of long-term low-concentration mixed benzene exposure on male peripheral blood in an automobile manufacturing enterprise].

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  • Author(s): Li YR;Li YR; Xie CJ; Qiu CX; Lin QY; Liu YM
  • Source:
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases [Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi] 2019 Feb 20; Vol. 37 (2), pp. 119-121.
  • Publication Type:
    Journal Article
  • Language:
    Chinese
  • Additional Information
    • Source:
      Publisher: Tianjin shi lao dong wei sheng yan jiu suo ; Tianjin shi lao dong wei sheng huan jing yi xue hui Country of Publication: China NLM ID: 8410840 Publication Model: Print Cited Medium: Print ISSN: 1001-9391 (Print) Linking ISSN: 10019391 NLM ISO Abbreviation: Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi
    • Publication Information:
      Original Publication: [Tientsin] : Tianjin shi lao dong wei sheng yan jiu suo ; Tianjin shi lao dong wei sheng huan jing yi xue hui, [1983-
    • Subject Terms:
      Automobiles* ; Manufacturing Industry*; Benzene/*toxicity ; Occupational Exposure/*adverse effects; Blood ; Case-Control Studies ; Humans ; Male ; Occupational Exposure/statistics & numerical data
    • Abstract:
      Objective: To investigated the effect of long - term low - concentration mixed benzene exposure on peripheral blood of male workers. Methods: A case - control study was conducted to select 452 male workers exposed to mixed benzene (benzene, toluene, xylene) for five consecutive years from January 2012 to December 2016 in an automobile manufacturer as case group, and 438 male administrative and logistic managers who underwent physical examination during the same period as control group. The peripheral blood of the two groups was tested and compared, and the occupational hazards in the workplace were detected. Results: There were low dose exposure to mixed benzene in the enterprise, but the test results met the occupational exposure limit requirements. During the five years from 2010 to 2016, between the two groups of workers, the mean values of WBC, NEUT, RBC and Hb were statistically different ( P <0.05). There was no statistical difference ( P >0.05) in the mean value of PLT. The abnormal rate of main peripheral blood indexes in the control group was higher than that in the exposed group. There were significant differences in NEUT, RBC and Hb ( P < 0.05), but no significant differences in WBC and PLT ( P >0.05). Conclusion: It can not be concluded that long - term low - concentration mixed benzene exposure can cause the change of peripheral blood index.
    • Grant Information:
      No.27[2016] Guangzhou Health and Family Planning Commission The Key Medical Disciplines and Specialities Program of Guangzhou; No.20[2012] Guangzhou Department "Twelfth Five-Year Plan" Medical Key Speciality of Guangdong Province; No.167[2011] Guangzhou Municipal Human Resources and Social Security Bureau "121 Talents Echelon project" Reserve Talent Program of Guangzhou
    • Contributed Indexing:
      Keywords: Benzene; Blood system; Low concentration; Male
      Local Abstract: [Publisher, Chinese] 目的： 探讨长期低浓度混苯接触对男性工人外周血的影响。 方法： 采用横断面调查方法，选取某汽车制造企业2012年1月~2016年12月连续5年均进行职业健康检查的452名接触混苯（苯、甲苯、二甲苯）男性工人作为接触组，选取同期进行职业体检的438名男性行政后勤管理人员作为对照组，比较两组人员的外周血检测结果，同时对作业场所职业病危害因素进行检测，以分析其相关关系。 结果： 2012~2016年，该汽车企业车间有低剂量的混苯暴露，但检测结果均符合职业接触限值要求。与对照组比较，接触组红细胞（WBC）、中性粒细胞（NENT）、红细胞（RBC）、血红蛋白（Hb）的均值差异均有统计学意义（ P < 0.05），血小板均值差异无统计学意义（ P >0.05）；与对照组比较，接触组外周血主要指标异常率低，NEUT、RBC、Hb指标差异有统计学意义（ P <0.05），WBC、PLT差异无统计学意义（ P >0.05）。 结论： 尚不能认为长期低浓度混苯接触可引起男性外周血指标的改变。.
    • Accession Number:
      J64922108F (Benzene)
    • Publication Date:
      Date Created: 20190401 Date Completed: 20190806 Latest Revision: 20190806
    • Publication Date:
      20221213
    • Accession Number:
      10.3760/cma.j.issn.1001-9391.2019.02.007
    • Accession Number:
      30929352