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Continuous co-production of biomass and bio-oxidized metabolite (sorbose) using Gluconobacter oxydans in a high-oxygen tension bioreactor.
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- Additional Information
- Source:
Publisher: Elsevier Applied Science Country of Publication: England NLM ID: 9889523 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2976 (Electronic) Linking ISSN: 09608524 NLM ISO Abbreviation: Bioresour Technol
- Publication Information:
Original Publication: Barking, Essex, England : New York, N.Y. : Elsevier Applied Science ; Elsevier Science Pub. Co., 1991-
- Subject Terms:
- Abstract:
High-efficiency cell proliferation of Gluconobacter oxydans was carried out in a compressed oxygen supply and sealed bioreactor to co-produce biomass and corresponding metabolite (sorbose). Higher cell density of Gluconobacter oxydans was achieved by implementing high-oxygen tension supply strategy resulting into high sorbose production from bio-oxidation of sorbitol. The highest biomass of 8.8 g/L and highest sorbose production of 432.8 g/L were simultaneously obtained after 72 h of fed-batch operation. Moreover, continuous co-production of biomass and sorbose was successfully conducted with retaining 10% sorbitol fermentation broth as the seed of next stage culture. The key features of this bioprocess application would enable cost-competitive Gluconobacter oxydans industrial applications.
(Copyright © 2019 Elsevier Ltd. All rights reserved.)
- Contributed Indexing:
Keywords: Biomass; COS-SSB; Gluconobacter oxydans NL71; Sorbitol; Sorbose
- Accession Number:
506T60A25R (Sorbitol)
NV2001607Y (Sorbose)
S88TT14065 (Oxygen)
- Publication Date:
Date Created: 20190120 Date Completed: 20190816 Latest Revision: 20190816
- Publication Date:
20221213
- Accession Number:
10.1016/j.biortech.2019.01.046
- Accession Number:
30658939
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