Incidence and Prevention of Biliary Leakage after Partial Liver Resection in a Tertiary Level Hospital.

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  • Author(s): Hasan MM;Hasan MM;Hasan MM; Zhen-Lin Y; Jun-Yong M
  • Source:
    Mymensingh medical journal : MMJ [Mymensingh Med J] 2018 Oct; Vol. 27 (4), pp. 737-745.
  • Publication Type:
    Journal Article; Observational Study
  • Language:
    English
  • Additional Information
    • Source:
      Publisher: Mymensingh Medical College Country of Publication: Bangladesh NLM ID: 9601799 Publication Model: Print Cited Medium: Internet ISSN: 2408-8757 (Electronic) Linking ISSN: 10224742 NLM ISO Abbreviation: Mymensingh Med J Subsets: MEDLINE
    • Publication Information:
      Original Publication: Mymensingh, Bangladesh : Mymensingh Medical College,
    • Subject Terms:
      Biliary Tract Diseases*/prevention & control ; Hepatectomy*/adverse effects ; Liver*/surgery; China ; Female ; Humans ; Incidence ; Male ; Postoperative Complications ; Retrospective Studies ; Risk Factors ; Treatment Outcome
    • Abstract:
      Biliary leakage is a postoperative complication of liver resection which may have considerable consequences. The aim of this study is to evaluate the incidence of post hepatectomy biliary leakage and to find out the preventive measures by systemic literature reviews. This observational study was conducted on 500 patients who required various forms of hepatic resection at the Department of Hepatic Surgery - 4, Eastern Hepatobiliary Surgery Hospital of The Second Military Medical University, Shanghai, China from September 2014 to July 2016. Out of 500 cases 413(82.6%) were males and 87(17.4%) females with female to male ratio 1:4.75. A total 23(4.6%) patients developed biliary leakage after surgery. Incidence of biliary leakage was more 21/440 (4.8%) in malignant diseases. Intrahepatic cholangio carcinoma had highest 4/23 (17.4%) incidence of biliary leakage among malignant diseases. It was lowest 2/60 (3.3%) in benign diseases. Non anatomical resection found to have higher incidence 5/17 (29.4%) of biliary leakage. Among the anatomical resection left extended hepatectomy found more porn 2/6 (33.3%) to develop biliary leakage. No biliary leakage test was done in 111(22.2%) patients to prevent biliary leakage. In other patients biliary leakage tests were carried out and there was not much variation in incidence of biliary leakage. Maximum patients 380(76%) were discharged from the hospital within 11-15 days after operation. Patients with biliary leakage had higher hospital stay. There are still no standardized methods to prevent biliary leakage because of the lack of clear evidence that support their use. Therefore, the development of novel technical strategies to reduce biliary leakage is required.
    • Publication Date:
      Date Created: 20181130 Date Completed: 20190510 Latest Revision: 20190510
    • Publication Date:
      20240829
    • Accession Number:
      30487488