[Biochemical markers of early diagnosis of occupationally related arterial hypertension in workers of ore-dressing production].

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  • Additional Information
    • Source:
      Publisher: Redkollegiia Zhurnala Country of Publication: Russia (Federation) NLM ID: 9434213 Publication Model: Print Cited Medium: Print ISSN: 1026-9428 (Print) Linking ISSN: 10269428 NLM ISO Abbreviation: Med Tr Prom Ekol Subsets: MEDLINE
    • Publication Information:
      Publication: Moskva : Redkollegiia Zhurnala
      Original Publication: Moskva : Redkollegiia zhurnala, 1993-
    • Subject Terms:
      Extraction and Processing Industry*; Hypertension/*blood ; Occupational Diseases/*blood ; Occupational Exposure/*analysis; Adult ; Air Pollutants, Occupational/adverse effects ; Air Pollutants, Occupational/analysis ; Biomarkers/blood ; Early Diagnosis ; Female ; Humans ; Hypertension/etiology ; Male ; Occupational Diseases/etiology ; Russia
    • Abstract:
      The authors demonstrate that work conditions for main occupations of sylvinite ore-dressing production (drying machine operator, granulation operator, drying and granulation dosage department operator, centrifuge operator, filtration operator, transporting machine operator in drying and granulation department, mill operator) are characterized by combined exposure to chemical and physical occupational hazards: formaldehyde, highly dispersed dust (PM,0), industrial noise, increased microclimate parameters. The work conditions are considered as hazardous (class 3.1, 3.2, 3.3). Findings are reliable increase of MDA level with lower general antioxidant defence in serum, when compared to the reference group. Increased homocysteine, lipoprotein with significant decreased nitrogen oxide production are seen. These processes can result in disordered structure and endothelial function of vessels, with higher prevalence of arterial hypertension. Values of MDA, antioxidant activity, homocysteine, lipoprotein (a), nitrogen oxide are justified as markers for early diagnosis of occupationally related arterial hypertension.
    • Accession Number:
      0 (Air Pollutants, Occupational)
      0 (Biomarkers)
    • Publication Date:
      Date Created: 20181024 Date Completed: 20190115 Latest Revision: 20190115
    • Publication Date:
      20221213
    • Accession Number:
      30351751