[Forecasting a risk of occupationally related diseases in workers engaged into titanium-magnesium production].

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  • Additional Information
    • Source:
      Publisher: Redkollegiia Zhurnala Country of Publication: Russia (Federation) NLM ID: 9434213 Publication Model: Print Cited Medium: Print ISSN: 1026-9428 (Print) Linking ISSN: 10269428 NLM ISO Abbreviation: Med Tr Prom Ekol Subsets: MEDLINE
    • Publication Information:
      Publication: Moskva : Redkollegiia Zhurnala
      Original Publication: Moskva : Redkollegiia zhurnala, 1993-
    • Subject Terms:
      Hypertension*/epidemiology ; Hypertension*/etiology ; Metallurgy* ; Occupational Diseases*/epidemiology ; Occupational Diseases*/etiology; Air Pollutants, Occupational/*analysis ; Noise, Occupational/*adverse effects ; Workload/*standards; Adult ; Case-Control Studies ; Forecasting ; Humans ; Models, Theoretical ; Risk ; Russia
    • Abstract:
      Workers of titanium and magnesium production, under occupational exposure to complex of chemical (chlorine, hydrochloride, sulfur dioxide) and physical factors (industrial noise, work hardiness), have arterial hypertension as occupationally related disease, when length of service over 15 years (EF = 71,5%), and nasopharyngitis for length of service over 10 years (EF = 65%). Arterial hypertension risk is mostly associated with increased industrial noise level (F = 1621; R2 0.95; p < 0,001; noise 70,1 dB). Mathematic modelling of nasopharyngitis development probability demonstrated dependence of concentration of chlorine, hydrochloride, sulfur dioxide, chlorine and hydrochloride combination (F = 37-281; R2 = 0,37-0,73; p < 0.001; chlorine 0,63 mg/m3). Complex of parameters (leucocytosis, eosinophilia, increased IgA level), activated cellular immunity (increased CD 16+56+, CD3+CD25+) and absolute phagocytosis characterized nonspecific inflammatory reaction, immunity tension as a response to a complex of chemical factors of titanium and magnesium production. Markers of endoihelial dysfunction and cardiovascular risk (uric acid, VEGF, homocystein, LDLP) and stress marker (cortisol) demonstrate potential effect of occupational factors on vascular wall, metabolic processes and central nervous system, with involvement of
    • Accession Number:
      0 (Air Pollutants, Occupational)
    • Publication Date:
      Date Created: 20181024 Date Completed: 20190115 Latest Revision: 20190115
    • Publication Date:
      20231215
    • Accession Number:
      30351749