Effects of breeding center, age and parasite burden on fecal triiodothyronine levels in forest musk deer.

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  • Additional Information
    • Source:
      Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE
    • Publication Information:
      Original Publication: San Francisco, CA : Public Library of Science
    • Subject Terms:
      Aging/*metabolism ; Deer/*metabolism ; Deer/*parasitology ; Feces/*chemistry ; Intestinal Diseases, Parasitic/*metabolism ; Triiodothyronine/*analysis; Animal Husbandry ; Animals ; Breeding ; Diet ; Environment ; Enzyme-Linked Immunosorbent Assay ; Feces/parasitology ; Female ; Male ; Sex Characteristics
    • Abstract:
      The objective of this study was to evaluate the effects of sex, breeding center and age on fecal triiodothyronine levels in captive forest musk deer Moschus berezovskii, and to explore the age-intensity model of gastrointestinal parasites. Furthermore, the association between fecal triiodothyronine levels and parasite egg shedding was also analyzed. We collected musk deer fecal samples from two breeding centers located in Shaanxi and Sichuan province, China. Enzyme-linked immunosorbent assays were utilized to estimate the fecal triiodothyronine concentrations and profiles, and fecal parasite eggs or oocysts were counted using the McMaster technique. Female deer from both breeding centers consistently showed higher triiodothyronine concentrations than those observed in males, which indicates that a distinct physiology pattern occurs by sex. The triiodothyronine concentration in Sichuan breeding center was significantly higher than that in Shaanxi center for both sexes, suggesting that differences in environment, diet and management practices are likely to affect the metabolism. In addition, a negative relationship between triiodothyronine concentrations and age was found (r = - 0.75, p < 0.001), and parasite egg shedding was also negatively associated with age (r = - 0.51, p < 0.001), by which we can infer that older animals evolves a more developed immune system. Finally, a positive association between parasite egg shedding and triiodothyronine levels was found, which could be explained by the additional energy metabolism resulting from parasitic infection. Results from this study might suggest metabolic and immunological adaptations in forest musk deer. These baseline data could be used to unveil metabolic status and establish parasite control strategies, which has great potential in captive population management as well as their general health evaluations.
      Competing Interests: There is one commercial funder to declare: Zhangzhou Pien Tze Huang Pharmaceutical Co., Ltd. This company will not use data from this study to develop products, apply for patent, or do any other commercial operation. This does not alter the authors' adherence to all the PLOS ONE policies on sharing data and materials. The authors have no other competing interests to declare.
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    • Accession Number:
      06LU7C9H1V (Triiodothyronine)
    • Publication Date:
      Date Created: 20181002 Date Completed: 20190408 Latest Revision: 20190408
    • Publication Date:
      20240829
    • Accession Number:
      PMC6166975
    • Accession Number:
      10.1371/journal.pone.0205080
    • Accession Number:
      30273412