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Assessment of arsenic species in human hair, toenail and urine and their association with water and staple food.
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- Author(s): Rasheed H;Rasheed H; Kay P; Kay P; Slack R; Slack R; Gong YY; Gong YY
- Source:
Journal of exposure science & environmental epidemiology [J Expo Sci Environ Epidemiol] 2019 Sep; Vol. 29 (5), pp. 624-632. Date of Electronic Publication: 2018 Sep 27.- Publication Type:
Journal Article- Language:
English - Source:
- Additional Information
- Source: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101262796 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-064X (Electronic) Linking ISSN: 15590631 NLM ISO Abbreviation: J Expo Sci Environ Epidemiol Subsets: MEDLINE
- Publication Information: Original Publication: New York, NY : Nature Pub. Group, c2006-
- Subject Terms:
- Abstract: Arsenic intake from household drinking/cooking water and food may represent a significant exposure pathway to induce cancer and non-cancer health effects. This study is based on the human biomonitoring of 395 volunteers from 223 households with private water sources located in rural Punjab, Pakistan. This work has shown the relative contribution of water and staple food to arsenic intake and accumulation by multiple biological matrix measurements of inorganic and organic arsenic species, while accounting for potential confounders such as age, gender, occupation, and exposure duration of the study population. Multi-variable linear regression showed a strong significant relationship between total arsenic (tAs) intake from water and concentrations of tAs, inorganic arsenic (iAs), monomethylarsonic acid (MMA), dimethylarsinic acid (DMA) in urine and toenail samples. tAs intake from staple food (rice and wheat) also showed a strong significant relationship with hair tAs and iAs. The sole impact of staple food intake on biomarkers was assessed and a significant correlation was found with all of the urinary arsenic metabolites. Toenail was found to be the most valuable biomarker of past exposure to inorganic and organic arsenic species of dietary and metabolic origin.
- Contributed Indexing: Keywords: Dietary exposure; Dimethylarsonic acid; Monomethylarsonic acid; Toenail arsenic; Urinary arsenic metabolites
- Accession Number: 0 (Biomarkers)
0 (Water Pollutants, Chemical)
N712M78A8G (Arsenic) - Publication Date: Date Created: 20180929 Date Completed: 20200619 Latest Revision: 20200619
- Publication Date: 20240628
- Accession Number: 10.1038/s41370-018-0056-7
- Accession Number: 30262833
- Source:
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