Persistent left superior vena cava as an arrhythmogenic source in atrial fibrillation: results from a multicenter experience.

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  • Additional Information
    • Source:
      Publisher: Springer Country of Publication: Netherlands NLM ID: 9708966 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1572-8595 (Electronic) Linking ISSN: 1383875X NLM ISO Abbreviation: J Interv Card Electrophysiol Subsets: MEDLINE
    • Publication Information:
      Publication: Amsterdam : Springer
      Original Publication: Norwell, MA : Kluwer Academic Publishers, c1997-
    • Subject Terms:
      Atrial Fibrillation/*surgery ; Catheter Ablation/*methods ; Heart Defects, Congenital/*surgery ; Vena Cava, Superior/*abnormalities; Aged ; Atrial Fibrillation/diagnosis ; Cohort Studies ; Electrocardiography/methods ; Female ; Follow-Up Studies ; Heart Defects, Congenital/diagnostic imaging ; Humans ; Male ; Middle Aged ; Pulmonary Veins/surgery ; Quality of Life ; Retrospective Studies ; Treatment Outcome ; Vena Cava, Superior/surgery
    • Abstract:
      Background: Persistent left superior vena cava (PLSVC) is one of the most frequently reported congenital anomalies and may be an important source of trigger of atrial fibrillation (AF).
      Methods: This was a multicenter retrospective experience including 28 patients with PLSVC who were referred for catheter ablation for drug-refractory symptomatic AF. Pulmonary vein and PLSVC isolation were performed (3.5-mm open irrigated tip ablation catheter at maximum power of 20 W, maximum temperature 43 °C with flow rate of 17 ml/min). Clinical outcomes such as complications and long-term freedom from AF were measured.
      Results: The mean age of the population was 61 ± 8 years, 21% were females, and AF duration was 60 ± 33 months. Sixty-one percent paroxysmal AF (17/28), 25% (7/28) persistent AF, and 14% (4/28) had long-standing persistent AF. There were no major complications that required any intervention. PLSVC isolation was achieved in 96% (27/28). Freedom from AF at 1 year without antiarrhythmic drugs was seen in 75% (21/28) of patients.
      Conclusions: In PLSVC patients with AF, segmental isolation of PLSVC appears to be feasible and safe and can translate into favorable clinical outcomes.
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    • Contributed Indexing:
      Keywords: Atrial fibrillation; Congenital anomaly; Persistent left superior vena cava syndrome; Radiofrequency ablation
    • Publication Date:
      Date Created: 20180928 Date Completed: 20190628 Latest Revision: 20200225
    • Publication Date:
      20231215
    • Accession Number:
      10.1007/s10840-018-0444-x
    • Accession Number:
      30259306