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Immunological memory cells.
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- Additional Information
- Source:
Publisher: Termedia Country of Publication: Poland NLM ID: 9702239 Publication Model: Print-Electronic Cited Medium: Print ISSN: 1426-3912 (Print) Linking ISSN: 14263912 NLM ISO Abbreviation: Cent Eur J Immunol Subsets: PubMed not MEDLINE
- Publication Information:
Publication: Poznań : Termedia
Original Publication: Warsaw : The Society, 1996-
- Abstract:
This article reviews immunological memory cells, currently represented by T and B lymphocytes and natural killer (NK) cells, which determine a rapid and effective response against a second encounter with the same antigen. Among T lymphocytes, functions of memory cells are provided by their subsets: central memory, effector memory, tissue-resident memory, regulatory memory and stem memory T cells. Memory T and B lymphocytes have an essential role in the immunity against microbial pathogens but are also involved in autoimmunity and maternal-fetal tolerance. Furthermore, the evidence of immunological memory has been established for NK cells. NK cells can respond to haptens or viruses, which results in generation of antigen-specific memory cells. T, B and NK cells, which have a role in immunological memory, have been characterized phenotypically and functionally. During the secondary immune response, these cells are involved in the reaction against foreign antigens, including pathogens, and take part in autoimmune diseases, but also are crucial to immunological tolerance and vaccine therapy.
Competing Interests: The authors declare no conflict of interest.
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- Contributed Indexing:
Keywords: immunological memory; memory B cells; memory NK cells; memory T cells
- Publication Date:
Date Created: 20180824 Latest Revision: 20240330
- Publication Date:
20250114
- Accession Number:
PMC6102609
- Accession Number:
10.5114/ceji.2018.77390
- Accession Number:
30135633
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