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Mismatch repair protein expression in Amsterdam II criteria-positive patients in Taiwan.
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- Author(s): Chen, J. R.; Chiang, J. M.; Changchien, C. R.; Chen, J. S.; Tang, R. P.; Wang, J. Y.
- Source:
British Journal of Surgery; Jan2008, Vol. 95 Issue 1, p102-110, 9p, 2 Diagrams, 4 Charts
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- Abstract:
The article details a study which investigated the clinical presentations and frequency of hereditary non-polyposis colorectal cancer in Taiwan through the use of the Amsterdam II (AC-II) criteria and immunohistochemistry (IHC). Using AC-II, the authors screened 7108 patients with primary colorectal cancer registered in Chang Gung Memorial Hospital's Colorectal Cancer Registry. IHC was used to analysed the mismatch repair genes of the tumour specimens.
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