Ancient human parallel lineages within North America contributed to a coastal expansion.

Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

Publication: : Washington, DC : American Association for the Advancement of Science
Original Publication: New York, N.Y. : [s.n.] 1880-

Biological Evolution* ; Emigration and Immigration* ; Genome, Human*; Population/*genetics; California ; Humans ; Ontario

Little is known regarding the first people to enter the Americas and their genetic legacy. Genomic analysis of the oldest human remains from the Americas showed a direct relationship between a Clovis-related ancestral population and all modern Central and South Americans as well as a deep split separating them from North Americans in Canada. We present 91 ancient human genomes from California and Southwestern Ontario and demonstrate the existence of two distinct ancestries in North America, which possibly split south of the ice sheets. A contribution from both of these ancestral populations is found in all modern Central and South Americans. The proportions of these two ancestries in ancient and modern populations are consistent with a coastal dispersal and multiple admixture events.
(Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works.)

Comment in: Science. 2018 Jun 1;360(6392):964-965. (PMID: 29853673)

098051 United Kingdom WT_ Wellcome Trust; 647787 International ERC_ European Research Council

Date Created: 20180602 Date Completed: 20180810 Latest Revision: 20220129

20221213

10.1126/science.aar6851

29853687