[CORRELATION BETWEEN HEAT PAIN THRESHOLD DEGREE AND TRPV1 RECEPTOR PROTEIN LEVEL OVER VARIOUS PHASES OF THE OVARIAN-MENSTRUAL CYCLE].

Publisher: Assot︠s︡iat︠s︡ii︠a︡ delovoĭ pressy Gruzii Country of Publication: Georgia (Republic) NLM ID: 101218222 Publication Model: Print Cited Medium: Internet ISSN: 1512-0112 (Print) Linking ISSN: 15120112 NLM ISO Abbreviation: Georgian Med News Subsets: MEDLINE

Original Publication: Tbilisi : Nʹi︠u︡-Ĭork : Assot︠s︡iat︠s︡ii︠a︡ delovoĭ pressy Gruzii ; International Academy of Science, Education, Industry & Arts

Aggression/*physiology ; Follicular Phase/*physiology ; Luteal Phase/*physiology ; Ovary/*physiology ; Pain Threshold/*physiology ; TRPV Cation Channels/*genetics; Adolescent ; Adult ; Aggression/psychology ; Female ; Follicle Stimulating Hormone/blood ; Follicle Stimulating Hormone/genetics ; Follicular Phase/psychology ; Gene Expression Regulation ; Hot Temperature ; Humans ; Luteal Phase/psychology ; Luteinizing Hormone/blood ; Luteinizing Hormone/genetics ; Pain Threshold/psychology ; Progesterone/blood ; Prolactin/blood ; Prolactin/genetics ; Psychological Tests ; TRPV Cation Channels/blood

Numerous scientific studies demonstrating differences in pain sensitivity over various phases of the ovarian-menstrual cycle (OMC) in healthy women have been published in recent decades, but the basis for these differences is however still poorly understood. The aim of the current study was to assess the correlation between the heat pain threshold degree and the dynamics of TRPV1 (Transient receptor potential channeling subfamily V member1) receptor protein level, as well as aggression degree in healthy women in the follicular and luteal phases of OMC. An increased TRPV1 receptor protein level and a decreased thermal pain threshold were found in the luteal phase of the OMC. The study revealed a correlation of the progesterone level in the luteal phase with a degree of increase of TRPV1 level, as well as with the degree of decrease of heat pain threshold. The relationship between the degree of pain threshold, as well as TRPV1 level with follicle stimulating (FSH), luteinizing (LH) hormones and prolactin levels was not found. Also, there was no correlation between TRPV1 or heat pain threshold levels and aggression degree.

0 (TRPV Cation Channels)
0 (TRPV1 protein, human)
4G7DS2Q64Y (Progesterone)
9002-62-4 (Prolactin)
9002-67-9 (Luteinizing Hormone)
9002-68-0 (Follicle Stimulating Hormone)

Date Created: 20180327 Date Completed: 20181221 Latest Revision: 20181221

20231215

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