Characteristics of aorto-iliofemoral arterial tree according to aortic valve morphology in chinese patients considered for TAVR.

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  • Additional Information
    • Source:
      Publisher: Springer Country of Publication: United States NLM ID: 100969716 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-8312 (Electronic) Linking ISSN: 15695794 NLM ISO Abbreviation: Int J Cardiovasc Imaging Subsets: MEDLINE
    • Publication Information:
      Publication: [New York] : Springer
      Original Publication: Boston : Kluwer Academic Publishers, c2001-
    • Subject Terms:
      Aorta/*diagnostic imaging ; Aortic Valve/*diagnostic imaging ; Aortic Valve Stenosis/*diagnostic imaging ; Femoral Artery/*diagnostic imaging ; Iliac Artery/*diagnostic imaging ; Vascular Calcification/*diagnostic imaging; Aged ; Aged, 80 and over ; Aortic Valve/surgery ; Aortic Valve Stenosis/surgery ; China ; Female ; Humans ; Male ; Retrospective Studies ; Tomography, X-Ray Computed ; Transcatheter Aortic Valve Replacement
    • Abstract:
      To characterize the anatomy of aorto-iliofemoral arterial tree according to aortic valve phenotype by CT in patients referred for transcatheter aortic valve replacement (TAVR). We retrospectively enrolled 215 patients screened for TAVR who underwent CT. Dimensions, calcification, vascular tortuosity index score and other putative risk features of 13 different regions were evaluated for bicuspid aortic valve (BAV) and tricuspid aortic valve (TAV) morphology. The study consisted of 44% BAVs with younger age than TAVs. The dimensions of the annulus, sinus of Valsalva, ascending aorta and aortic arch were consistently larger in BAVs. The prevalence of calcification of aortic arch was significantly higher in TAVs even after adjustment for atherosclerotic risk factors. BAVs was associated with two-fold higher odds of having over I degree AA calcification (odds ratio 2.02; 95% CI 1.60-5.31; p < 0.001). The prevalence of severe iliac tortuosity was higher among BAVs (11.7 vs. 2.5%, p = 0.015). BAVs had a trend to more atheroma than TAVs in the abdominal aortic artery and iliofemoral artery. BAV anatomy is common in Chinese AS patients screened for TAVR. Aorto-iliofemoral pathology varies according to aortic valve phenotype, which may contribute to technical challenges in BAV vs. TAV anatomy and support the need for the integrated risk assessment for each valve phenotype.
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    • Grant Information:
      2016-1002-01-05 Pecking Union Medical College Student Innovation Fund
    • Contributed Indexing:
      Keywords: Aorta; Aortic valve; Aortic valve stenosis; Transcatheter aortic valve replacement; Vascular calcification
    • Publication Date:
      Date Created: 20180204 Date Completed: 20190429 Latest Revision: 20190429
    • Publication Date:
      20221213
    • Accession Number:
      10.1007/s10554-018-1310-8
    • Accession Number:
      29396829