[NEPHROTOXIC DRUGS].

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  • Author(s): Popović B; Šutić I; Marković NB
  • Source:
    Acta medica Croatica : casopis Hravatske akademije medicinskih znanosti [Acta Med Croatica] 2016 Dec; Vol. 70 (4-5), pp. 309-14.
  • Publication Type:
    Journal Article; Review
  • Language:
    Croatian
  • Additional Information
    • Source:
      Publisher: Croatian Academy Of Medical Sciences Country of Publication: Croatia NLM ID: 9208249 Publication Model: Print Cited Medium: Print ISSN: 1330-0164 (Print) Linking ISSN: 13300164 NLM ISO Abbreviation: Acta Med Croatica Subsets: MEDLINE
    • Publication Information:
      Publication: Zagreb : Croatian Academy Of Medical Sciences
      Original Publication: Zagreb : Hrvatska akademija medicinskih znanosti, [1991-
    • Subject Terms:
      Anti-Inflammatory Agents, Non-Steroidal/*adverse effects ; Protective Agents/*administration & dosage ; Renal Insufficiency, Chronic/*etiology ; Renal Insufficiency, Chronic/*prevention & control; Acute Kidney Injury/etiology ; Analgesics/adverse effects ; Analgesics, Non-Narcotic/adverse effects ; Biomarkers/blood ; Contrast Media/adverse effects ; Drug-Related Side Effects and Adverse Reactions ; Humans ; Renal Insufficiency, Chronic/blood
    • Abstract:
      Renal tissue is sensitive to the effect of potentially nephrotoxic drugs and other substances that are available over-the-counter or can be purchased at healthy food stores or elsewhere, and harmful substances from the environment. The harmful effects of these substances lead to the development of recognizable clinical syndromes, including acute or chronic renal failure, tubulopathy, and proteinuria. Risk factors that influence the development of kidney disease induced by drugs are divided into those related to patient characteristics, drug characteristics, and renal function. Drugs that commonly exhibit nephrotoxic effects are analgesics, antimicrobials, chemotherapeutics, contrast agents, immunosuppressants, herbal preparations and substances containing heavy metals. Family physician must carefully observe their patients, nurturing individual approach to drug selection and determining the dose. Renal function can quickly return to normal if the damage is recognized on time. Recent research yields insights into the identification of new biomarkers that will contribute to early detection of drug induced kidney damage.
    • Accession Number:
      0 (Analgesics)
      0 (Analgesics, Non-Narcotic)
      0 (Anti-Inflammatory Agents, Non-Steroidal)
      0 (Biomarkers)
      0 (Contrast Media)
      0 (Protective Agents)
    • Publication Date:
      Date Created: 20171101 Date Completed: 20171207 Latest Revision: 20181202
    • Publication Date:
      20240628
    • Accession Number:
      29087164