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BAK linked to ocular surlace damage in animal studies.
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- Author(s): Kahook, Malik
- Source:
Ophthalmology Times. 1/15/2008, Vol. 33 Issue 2, p30-31. 2p.
- Subject Terms:
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- Subject Terms:
- Abstract:
The article reports on the study conducted in an animal model with medication preserved with benzalkonium chloride (BAK) in Taormina, Italy. Researchers found that latanoprost with BAK caused a significant loss of cell-cell adhesion that can predispose patients to have ocular surface damage. It revealed that once-daily dosing of latanoprost with 0.02% BAK produced more goblet cell loss compared with either preservative-free-artificial tear or travoprost ophthalmic solution.
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