Role of Polyethylene Glycol in the Treatment of Functional Constipation in Children.

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  • Additional Information
    • Source:
      Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 8211545 Publication Model: Print Cited Medium: Internet ISSN: 1536-4801 (Electronic) Linking ISSN: 02772116 NLM ISO Abbreviation: J Pediatr Gastroenterol Nutr Subsets: MEDLINE
    • Publication Information:
      Publication: 1998- : Philadelphia, PA : Lippincott Williams & Wilkins
      Original Publication: [New York, N.Y.] : Raven Press, [c1982-
    • Subject Terms:
      Constipation/*drug therapy ; Laxatives/*therapeutic use ; Polyethylene Glycols/*therapeutic use; Child ; Contraindications, Drug ; Drug Compounding ; Drug Dosage Calculations ; Humans ; Laxatives/adverse effects ; Polyethylene Glycols/adverse effects ; Treatment Outcome
    • Abstract:
      According to international guidelines, polyethylene glycol (PEG) is the laxative of first choice in the treatment of functional constipation in children, both for disimpaction and for maintenance treatment. PEG acts as an osmotic laxative and its efficacy is dose dependent. PEG is highly effective, has a good safety profile, and is well tolerated by children. Only minor adverse events have been reported. Overall the use of PEG in children has been reported to be safe, although in patients predisposed to water and electrolyte imbalances monitoring of serum electrolytes should be considered.
    • Accession Number:
      0 (Laxatives)
      3WJQ0SDW1A (Polyethylene Glycols)
    • Publication Date:
      Date Created: 20170805 Date Completed: 20180424 Latest Revision: 20220317
    • Publication Date:
      20231215
    • Accession Number:
      10.1097/MPG.0000000000001704
    • Accession Number:
      28777126