[Multiparametric MRI of the prostate : Important radiological findings for urologists].

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  • Author(s): Schlemmer HP;Schlemmer HP
  • Source:
    Der Radiologe [Radiologe] 2017 Aug; Vol. 57 (8), pp. 621-630.
  • Publication Type:
    Journal Article; Review
  • Language:
    German
  • Additional Information
    • Transliterated Title:
      Multiparametrische MRT der Prostata : Wichtige radiologische Befunde für den Urologen.
    • Source:
      Publisher: Springer Verlag Country of Publication: Germany NLM ID: 0401257 Publication Model: Print Cited Medium: Internet ISSN: 1432-2102 (Electronic) Linking ISSN: 0033832X NLM ISO Abbreviation: Radiologe Subsets: MEDLINE
    • Publication Information:
      Original Publication: Berlin : Springer Verlag
    • Subject Terms:
      Urologists*; Magnetic Resonance Imaging/*methods ; Prostate/*diagnostic imaging ; Prostatic Neoplasms/*diagnostic imaging; Contrast Media ; Humans ; Image-Guided Biopsy/methods ; Male ; Prostate/pathology ; Prostate-Specific Antigen/blood ; Prostatic Neoplasms/blood ; Prostatic Neoplasms/pathology
    • Abstract:
      Clinical/methodical Issue: High prevalence of prostate cancer with multifocality and biological heterogeneity. Insufficient conventional urological diagnostics. Discrimination between significant and insignificant cancer needed.
      Standard Diagnostic Methods: Digital rectal examination, prostate-specific antigen (PSA) serum level, systematic transrectal ultrasound (TRUS)-guided prostate biopsy.
      Methodical Innovations: Multiparametric magnetic resonance imaging (mpMRI) including T2-weighted (T2w), diffusion-weighted and dynamic contrast-enhanced MRI according to the prostate imaging reporting and data system (PIRADS), MR-targeted biopsy, most frequently MR/TRUS image fusion biopsy.
      Findings and Performance: Prostate cancer is characterized by low signal intensity on T2w MRI, restricted water diffusion and pronounced and early uptake of contrast enhancement. Sensitivity and specificity according to the current literature are ca. 80% and 90%, respectively.
      Practical Recommendations: In cases of suspected prostate cancer, most accurate are mpMRI according to PIRADS and in cases of positive findings, MRI-targeted biopsy, most frequently as MRI/TRUS image fusion biopsy.
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    • Contributed Indexing:
      Keywords: Multiparametric MRI; PIRADS; Prostate cancer
    • Accession Number:
      0 (Contrast Media)
      EC 3.4.21.77 (Prostate-Specific Antigen)
    • Publication Date:
      Date Created: 20170702 Date Completed: 20180409 Latest Revision: 20220316
    • Publication Date:
      20221213
    • Accession Number:
      10.1007/s00117-017-0277-0
    • Accession Number:
      28667392