Four new iridoid glucosides containing the furan ring from the fruit of Cornus officinalis.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 16930290R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-6971 (Electronic) Linking ISSN: 0367326X NLM ISO Abbreviation: Fitoterapia Subsets: MEDLINE
    • Publication Information:
      Publication: 1999- : [Amsterdam] : Elsevier
      Original Publication: Milano : Inverni & Della Beffa S.p.A.
    • Subject Terms:
      Cornus/*chemistry ; Fruit/*chemistry ; Iridoid Glucosides/*chemistry ; Neuroprotective Agents/*chemistry; Animals ; Iridoid Glucosides/isolation & purification ; Molecular Structure ; Neuroprotective Agents/isolation & purification ; PC12 Cells ; Rats
    • Abstract:
      Four new and rare iridoid glucosides, cornusfuroside A-D (1-4), containing the furan ring were identified from water extract of the fruit of Cornus officinalis. These new chemical structures were determined through extensive spectroscopic analysis, including 1D and 2D NMR, IR, HRESIMS, experimental and calculated electronic circular dichroism (ECD). Notably, this study is the first report on the isolation of four iridoid glucoside structures with acetal functions in the sugar moiety. The neuroprotective effects of these compounds were also evaluated in vitro.
      (Copyright © 2017 Elsevier B.V. All rights reserved.)
    • Contributed Indexing:
      Keywords: Cornus officinalis; Cornusfuroside A–D; Furan ring; Neuroprotective effect
    • Accession Number:
      0 (Iridoid Glucosides)
      0 (Neuroprotective Agents)
    • Publication Date:
      Date Created: 20170610 Date Completed: 20170731 Latest Revision: 20170731
    • Publication Date:
      20240829
    • Accession Number:
      10.1016/j.fitote.2017.06.003
    • Accession Number:
      28596026