Circulating thyroid hormones and associated metabolites in white whales (Delphinapterus leucas) determined using isotope-dilution mass spectrometry.

Item request has been placed! ×
Item request cannot be made. ×
loading   Processing Request
Read More Add to Saved list
  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0147621 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0953 (Electronic) Linking ISSN: 00139351 NLM ISO Abbreviation: Environ Res Subsets: MEDLINE
    • Publication Information:
      Publication: <2000- > : Amsterdam : Elsevier
      Original Publication: New York, Academic Press.
    • Subject Terms:
      Chromatography, Liquid* ; Mass Spectrometry*; Beluga Whale/*metabolism ; Blood Chemical Analysis/*methods ; Thyroid Hormones/*blood; Animals ; Female ; Male ; Plasma/chemistry ; Serum/chemistry ; Svalbard ; Thyroid Hormones/metabolism
    • Abstract:
      Blood was sampled from nine free-ranging white whales (beluga whale, Delphinapterus leucas) from Svalbard, Norway during the summers of 2013 and 2014. Total concentrations of eleven thyroid hormones and metabolites were measured in serum using a novel liquid chromatography tandem mass spectrometry analytical method. Measurements of these compounds in plasma gave the same results as in serum. The three hormones found in highest concentrations were 3,3',5-triiodothyronine (T 3 ), 3,3',5'-triiodothyronine (rT 3 ) and thyroxine (T 4 ). Traces of associated metabolites were also found.
      (Copyright © 2017 Elsevier Inc. All rights reserved.)
    • Contributed Indexing:
      Keywords: Beluga whale; Endocrine disruption; LC-MS/MS; Reverse-T(3); Thyronamines
    • Accession Number:
      0 (Thyroid Hormones)
    • Publication Date:
      Date Created: 20170326 Date Completed: 20170623 Latest Revision: 20171119
    • Publication Date:
      20231215
    • Accession Number:
      10.1016/j.envres.2017.03.027
    • Accession Number:
      28342348