Effect of fenbendazole in water on pigs infected with Ascaris suum in finishing pigs under field conditions.

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  • Additional Information
    • Source:
      Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7602745 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2550 (Electronic) Linking ISSN: 03044017 NLM ISO Abbreviation: Vet Parasitol Subsets: MEDLINE
    • Publication Information:
      Publication: Amsterdam : Elsevier
      Original Publication: Amsterdam : Elsevier Scientific Pub. Co.
    • Subject Terms:
      Anthelmintics/*administration & dosage ; Ascariasis/*veterinary ; Ascaris suum/*drug effects ; Fenbendazole/*administration & dosage ; Swine Diseases/*drug therapy; Animals ; Ascariasis/drug therapy ; Ascariasis/parasitology ; Feces/parasitology ; Female ; Liver/parasitology ; Ovum ; Parasite Egg Count/veterinary ; Red Meat/standards ; Swine ; Swine Diseases/parasitology ; Water ; Weight Gain/drug effects
    • Abstract:
      The husbandry of pigs for meat production is a constantly developing industry. Most studies on the effects of Ascaris suum infection in pigs and its prevention with anthelmintics are over a decade old. We examined the effect of 2.5mg fenbendazole per kg bodyweight administered in drinking water for two consecutive days on A. suum infection 1 and 6 weeks after pigs arrived to fattening units. We hypothesised that the treatment would reduce the presence of A. suum-infections, improve the average daily weight gain of pigs, reduce the percentage of liver rejections in pens by 50% and increase the lean meat percentage at slaughter by 1%. The study included a placebo group (427 pigs) and a treatment group (420 pigs) spanning four different farms previously reporting ≥15% liver rejection. The treatment was given for 2 consecutive days 1 and 6 weeks after the pigs arrived to the fattening unit. Faecal samples were collected during weeks 1, 6 and 12 from all pigs and examined for A. suum eggs. Blood was collected during weeks 1 and 12 from a subgroup of the pigs and examined for anti-A. suum antibodies and clinical blood parameters. Data on liver rejection and lean meat percentage were collected post-mortem. The proportion of Ascaris seropositive pigs changed from 8.6% to 22.2% and 20.3% to 16.3% in the placebo and treatment group respectively. Fenbendazole reduced the presence of A. suum eggs in faeces the percentage of liver rejections by 69.8%. The treatment did not affect daily weight gain or lean meat percentage. Pigs with A. suum eggs in faeces at week 6 had a lower average daily weight gain of 61.8g/day compared with pigs without parasite eggs. Fenbendazole treatment may be a useful option for farms struggling with persistent A. suum problems and demonstrate a beneficial effect on the weight gain of the animals shedding eggs in faeces and result in fewer condemned livers at slaughter.
      (Copyright © 2017 Elsevier B.V. All rights reserved.)
    • Contributed Indexing:
      Keywords: Anthelmintic; Ascaris suum; Fenbendazole; Liver rejection; Milk spots; Swine
    • Accession Number:
      0 (Anthelmintics)
      059QF0KO0R (Water)
      621BVT9M36 (Fenbendazole)
    • Publication Date:
      Date Created: 20170314 Date Completed: 20170926 Latest Revision: 20170926
    • Publication Date:
      20240829
    • Accession Number:
      10.1016/j.vetpar.2017.03.005
    • Accession Number:
      28285891