Post-translational modifications of FLOWERING LOCUS C modulate its activity.

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  • Additional Information
    • Source:
      Publisher: Oxford University Press Country of Publication: England NLM ID: 9882906 Publication Model: Print Cited Medium: Internet ISSN: 1460-2431 (Electronic) Linking ISSN: 00220957 NLM ISO Abbreviation: J Exp Bot Subsets: MEDLINE
    • Publication Information:
      Original Publication: Oxford, UK : Oxford University Press,
    • Subject Terms:
      Gene Expression Regulation, Plant* ; Protein Processing, Post-Translational*; Arabidopsis/*genetics ; Arabidopsis/*growth & development ; Arabidopsis Proteins/*genetics ; Flowers/*growth & development ; MADS Domain Proteins/*genetics; Arabidopsis/metabolism ; Arabidopsis Proteins/metabolism ; Flowers/metabolism ; MADS Domain Proteins/metabolism
    • Abstract:
      Flowering Locus C (FLC) is a key floral repressor that precisely controls flowering time. The role of FLC has been extensively studied at the transcriptional level using molecular biological and epigenetic approaches. However, how FLC functions and how its stability is controlled at the post-translational level are only beginning to be understood. Recent studies show that various post-translational modifications (PTMs) control the stability and activity of FLC. In this review, we focus on three types of PTMs that regulate FLC function: phosphorylation, ubiquitination, and sumoylation. This report should serve as a model to guide post-translational studies of other important floral regulators.
    • Contributed Indexing:
      Keywords: FLC; flowering; phosphorylation; post-translational modification; sumoylation; ubiquitination
    • Accession Number:
      0 (Arabidopsis Proteins)
      0 (FLF protein, Arabidopsis)
      0 (MADS Domain Proteins)
    • Publication Date:
      Date Created: 20170217 Date Completed: 20180710 Latest Revision: 20180719
    • Publication Date:
      20231215
    • Accession Number:
      10.1093/jxb/erw431
    • Accession Number:
      28204510