[Fatal thrombocytopenia triggered by quinidine].

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  • Author(s): Rohold A; Nielsen HL; Hasle H
  • Source:
    Ugeskrift for laeger [Ugeskr Laeger] 1989 Oct 09; Vol. 151 (41), pp. 2672.
  • Publication Type:
    Case Reports; English Abstract; Journal Article
  • Language:
    Danish
  • Additional Information
    • Transliterated Title:
      Kinidinudløst trombocytopeni med letalt forløb.
    • Source:
      Publisher: Den Alm Danske Laegerforening Country of Publication: Denmark NLM ID: 0141730 Publication Model: Print Cited Medium: Print ISSN: 0041-5782 (Print) Linking ISSN: 00415782 NLM ISO Abbreviation: Ugeskr Laeger Subsets: MEDLINE
    • Publication Information:
      Original Publication: Copenhagen : Den Alm Danske Laegerforening
    • Subject Terms:
      Quinidine/*adverse effects ; Thrombocytopenia/*chemically induced; Cerebral Hemorrhage/chemically induced ; Female ; Humans ; Middle Aged ; Phenprocoumon/adverse effects
    • Abstract:
      A woman aged 60 years receiving anticoagulation treatment on account of artificial mitral and aortic valve prostheses developed severe thrombocytopenia three weeks after the commencement of quinidine treatment. The results of investigations suggested severe thrombocytopenia precipitated by quinidine. The severe thrombocytopenia persisted despite intensive treatment and the condition ended fatally on account of cerebral haemorrhage. The combination of quinidine and oral anticoagulation treatment is not unusual and it is important to bear in mind that both of these preparations may cause increased haemorrhagic tendencies.
    • Accession Number:
      ITX08688JL (Quinidine)
      Q08SIO485D (Phenprocoumon)
    • Publication Date:
      Date Created: 19891009 Date Completed: 19891205 Latest Revision: 20131121
    • Publication Date:
      20221213
    • Accession Number:
      2815384