Menu
×
Folly Beach Library
9 a.m. - 5:30 p.m.
Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
West Ashley Library
9 a.m. - 7 p.m.
Phone: (843) 766-6635
Wando Mount Pleasant Library
9 a.m. - 8 p.m.
Phone: (843) 805-6888
Village Library
9 a.m. - 6 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
9 a.m. - 8 p.m.
Phone: (843) 889-3300
Otranto Road Library
9 a.m. - 8 p.m.
Phone: (843) 572-4094
Mt. Pleasant Library
9 a.m. - 8 p.m.
Phone: (843) 849-6161
McClellanville Library
9 a.m. - 6 p.m.
Phone: (843) 887-3699
Keith Summey North Charleston Library
9 a.m. - 8 p.m.
Phone: (843) 744-2489
John's Island Library
9 a.m. - 8 p.m.
Phone: (843) 559-1945
Hurd/St. Andrews Library
9 a.m. - 8 p.m.
Phone: (843) 766-2546
Miss Jane's Building (Edisto Library Temporary Location)
9 a.m. - 4 p.m.
Phone: (843) 869-2355
Dorchester Road Library
9 a.m. - 8 p.m.
Phone: (843) 552-6466
John L. Dart Library
9 a.m. - 7 p.m.
Phone: (843) 722-7550
Baxter-Patrick James Island
9 a.m. - 8 p.m.
Phone: (843) 795-6679
Main Library
9 a.m. - 8 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
9 a.m. - 8 p.m.
Phone: (843) 805-6892
Mobile Library
9 a.m. - 5 p.m.
Phone: (843) 805-6909
Today's Hours
Folly Beach Library
9 a.m. - 5:30 p.m.
Phone: (843) 588-2001
Edgar Allan Poe/Sullivan's Island Library
Closed for renovations
Phone: (843) 883-3914
West Ashley Library
9 a.m. - 7 p.m.
Phone: (843) 766-6635
Wando Mount Pleasant Library
9 a.m. - 8 p.m.
Phone: (843) 805-6888
Village Library
9 a.m. - 6 p.m.
Phone: (843) 884-9741
St. Paul's/Hollywood Library
9 a.m. - 8 p.m.
Phone: (843) 889-3300
Otranto Road Library
9 a.m. - 8 p.m.
Phone: (843) 572-4094
Mt. Pleasant Library
9 a.m. - 8 p.m.
Phone: (843) 849-6161
McClellanville Library
9 a.m. - 6 p.m.
Phone: (843) 887-3699
Keith Summey North Charleston Library
9 a.m. - 8 p.m.
Phone: (843) 744-2489
John's Island Library
9 a.m. - 8 p.m.
Phone: (843) 559-1945
Hurd/St. Andrews Library
9 a.m. - 8 p.m.
Phone: (843) 766-2546
Miss Jane's Building (Edisto Library Temporary Location)
9 a.m. - 4 p.m.
Phone: (843) 869-2355
Dorchester Road Library
9 a.m. - 8 p.m.
Phone: (843) 552-6466
John L. Dart Library
9 a.m. - 7 p.m.
Phone: (843) 722-7550
Baxter-Patrick James Island
9 a.m. - 8 p.m.
Phone: (843) 795-6679
Main Library
9 a.m. - 8 p.m.
Phone: (843) 805-6930
Bees Ferry West Ashley Library
9 a.m. - 8 p.m.
Phone: (843) 805-6892
Mobile Library
9 a.m. - 5 p.m.
Phone: (843) 805-6909
Patron Login
menu
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
Evaluating surrogate marker information using censored data.
Item request has been placed!
×
Item request cannot be made.
×
![loading](/sites/all/modules/hf_eds/images/loading.gif)
- Author(s): Parast L;Parast L; Cai T; Cai T; Tian L; Tian L
- Source:
Statistics in medicine [Stat Med] 2017 May 20; Vol. 36 (11), pp. 1767-1782. Date of Electronic Publication: 2017 Jan 15.- Publication Type:
Journal Article; Research Support, U.S. Gov't, P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't- Language:
English - Source:
- Additional Information
- Source: Publisher: Wiley Country of Publication: England NLM ID: 8215016 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0258 (Electronic) Linking ISSN: 02776715 NLM ISO Abbreviation: Stat Med Subsets: MEDLINE
- Publication Information: Original Publication: Chichester ; New York : Wiley, c1982-
- Subject Terms:
- Abstract: Given the long follow-up periods that are often required for treatment or intervention studies, the potential to use surrogate markers to decrease the required follow-up time is a very attractive goal. However, previous studies have shown that using inadequate markers or making inappropriate assumptions about the relationship between the primary outcome and surrogate marker can lead to inaccurate conclusions regarding the treatment effect. Currently available methods for identifying and validating surrogate markers tend to rely on restrictive model assumptions and/or focus on uncensored outcomes. The ability to use such methods in practice when the primary outcome of interest is a time-to-event outcome is difficult because of censoring and missing surrogate information among those who experience the primary outcome before surrogate marker measurement. In this paper, we propose a novel definition of the proportion of treatment effect explained by surrogate information collected up to a specified time in the setting of a time-to-event primary outcome. Our proposed approach accommodates a setting where individuals may experience the primary outcome before the surrogate marker is measured. We propose a robust non-parametric procedure to estimate the defined quantity using censored data and use a perturbation-resampling procedure for variance estimation. Simulation studies demonstrate that the proposed procedures perform well in finite samples. We illustrate the proposed procedures by investigating two potential surrogate markers for diabetes using data from the Diabetes Prevention Program. Copyright © 2017 John Wiley & Sons, Ltd.
(Copyright © 2017 John Wiley & Sons, Ltd.) - References: Stat Med. 2015 Feb 10;34(3):381-95. (PMID: 25352131)
J Clin Oncol. 2014 Aug 1;32(22):2380-5. (PMID: 24982461)
Diabetes Care. 1999 Apr;22(4):623-34. (PMID: 10189543)
Br J Cancer. 1999 Mar;79(9-10):1522-30. (PMID: 10188901)
Biometrics. 2002 Mar;58(1):21-9. (PMID: 11890317)
Stat Med. 1989 Apr;8(4):431-40. (PMID: 2727467)
JAMA. 2006 Jun 7;295(21):2511-5. (PMID: 16757723)
Biometrics. 2013 Sep;69(3):561-9. (PMID: 24073861)
Lifetime Data Anal. 2011 Oct;17(4):552-65. (PMID: 21455700)
Biostatistics. 2015 Apr;16(2):400-12. (PMID: 25236906)
Biostatistics. 2014 Apr;15(2):251-65. (PMID: 24337534)
Biostatistics. 2014 Apr;15(2):266-83. (PMID: 24285772)
Epidemiology. 1992 Mar;3(2):143-55. (PMID: 1576220)
Biostatistics. 2012 Apr;13(2):256-73. (PMID: 22294672)
Stat Med. 2011 Aug 30;30(19):2409-21. (PMID: 21611958)
Biometrics. 2011 Dec;67(4):1442-51. (PMID: 21517791)
Stat Med. 1997 Jul 15;16(13):1515-27. (PMID: 9249922)
Biometrics. 2008 Mar;64(1):149-56. (PMID: 17651457)
Biometrics. 2002 Dec;58(4):803-12. (PMID: 12495134)
Stat Med. 2016 May 10;35(10 ):1637-53. (PMID: 26631934)
JAMA. 1999 Aug 25;282(8):790-5. (PMID: 10463719)
Stat Med. 1992 Jan 30;11(2):167-78. (PMID: 1579756)
Biometrics. 2008 Sep;64(3):707-15. (PMID: 18190618)
N Engl J Med. 2002 Feb 7;346(6):393-403. (PMID: 11832527)
Biometrics. 1998 Sep;54(3):1014-29. (PMID: 9840970)
Biostatistics. 2014 Apr;15(2):222-33. (PMID: 24292992)
Stat Methods Med Res. 2017 Feb;26(1):88-107. (PMID: 24947559)
Biometrics. 2008 Dec;64(4):1146-54. (PMID: 18363776)
Clin Trials. 2012 Oct;9(5):570-7. (PMID: 22914867)
Biometrics. 2009 Jun;65(2):521-9. (PMID: 18759839)
JAMA. 2001 Jan 10;285(2):190-2. (PMID: 11176812) - Grant Information: R01 DK118354 United States DK NIDDK NIH HHS; R21 DK103118 United States DK NIDDK NIH HHS; U54 HG007963 United States HG NHGRI NIH HHS; United States CC CDC HHS
- Contributed Indexing: Keywords: non-parametric methods; robust procedures; smoothing; survival analysis
- Accession Number: 0 (Biomarkers)
- Publication Date: Date Created: 20170116 Date Completed: 20180308 Latest Revision: 20210508
- Publication Date: 20221213
- Accession Number: PMC5413393
- Accession Number: 10.1002/sim.7220
- Accession Number: 28088843
- Source:
Contact CCPL
Copyright 2022 Charleston County Public Library Powered By EBSCO Stacks 3.3.0 [350.3] | Staff Login
No Comments.