Glucagon like peptide-1 and its receptor agonists: Their roles in management of Type 2 diabetes mellitus.

Publisher: Elsevier Ltd Country of Publication: Netherlands NLM ID: 101462250 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-0334 (Electronic) Linking ISSN: 18714021 NLM ISO Abbreviation: Diabetes Metab Syndr Subsets: MEDLINE

Original Publication: Amsterdam : Elsevier Ltd.

Disease Management*; Diabetes Mellitus, Type 2/*drug therapy ; Glucagon-Like Peptide 1/*agonists ; Glucagon-Like Peptide-1 Receptor/*agonists ; Hypoglycemic Agents/*therapeutic use; Amino Acid Sequence ; Diabetes Mellitus, Type 2/blood ; Diabetes Mellitus, Type 2/genetics ; Glucagon-Like Peptide 1/physiology ; Glucagon-Like Peptide-1 Receptor/physiology ; Humans ; Hypoglycemic Agents/pharmacology

This study summarizes major work which investigated the roles of glucagon like peptide-1 (GLP-1) and its receptor (GLP-1R); the use of GLP-1-R agonists and dipeptidyl peptidase 4 inhibitor in the management of type 2 diabetes mellitus. It focuses on the recent therapeutic development which has occurred in this field, and also discusses the potential treatments which can be discovered and implemented in the near future to design an effective therapy for type 2 diabetes mellitus.
(Copyright © 2016 Diabetes India. Published by Elsevier Ltd. All rights reserved.)

Keywords: Dipeptidyl peptidase inhibitors; Glucagon like peptide-1; Type 2 diabetes mellitus

0 (Glucagon-Like Peptide-1 Receptor)
0 (Hypoglycemic Agents)
89750-14-1 (Glucagon-Like Peptide 1)

Date Created: 20161126 Date Completed: 20180418 Latest Revision: 20180418

20221213

10.1016/j.dsx.2016.09.003

27884496