Item request has been placed!
×
Item request cannot be made.
×
Processing Request
Maternal diet quality before pregnancy and risk of childhood leukaemia.
Item request has been placed!
×
Item request cannot be made.
×
Processing Request
- Additional Information
- Source:
Publisher: Published on behalf of the Nutrition Society by CABI Publishing Country of Publication: England NLM ID: 0372547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2662 (Electronic) Linking ISSN: 00071145 NLM ISO Abbreviation: Br J Nutr Subsets: MEDLINE
- Publication Information:
Publication: <2000->: Wallingford, Oxon, UK : Published on behalf of the Nutrition Society by CABI Publishing
Original Publication: [Cambridge, New York] Cambridge University Press.
- Subject Terms:
- Abstract:
Previous studies on maternal nutrition and childhood leukaemia risk have focused on the role of specific nutrients such as folate and have not considered broader measures of diet quality, which may better capture intake of diverse nutrients known to impact fetal development. We examined the relationship between maternal diet quality before pregnancy, as summarised by a diet quality index, and risk of childhood acute lymphoblastic leukaemia (ALL) and acute myeloid leukaemia (AML) in a case-control study in California. Dietary intake in the year before pregnancy was assessed using FFQ in 681 ALL cases, 103 AML cases and 1076 matched controls. Conditional logistic regression was used to estimate OR and 95 % CI for diet quality continuous score and quartiles (Q1-Q4). Higher maternal diet quality score was associated with reduced risk of ALL (OR 0·66; 95 % CI 0·47, 0·93 for Q4 v. Q1) and possibly AML (OR 0·42; 95 % CI 0·15, 1·15 for Q4 v. Q1). No single index component appeared to account for the association. The association of maternal diet quality with risk of ALL was stronger in children diagnosed under the age of 5 years and in children of women who did not report using vitamin supplements before pregnancy. These findings suggest that the joint effects of many dietary components may be important in influencing childhood leukaemia risk.
- Contributed Indexing:
Keywords: ALL acute lymphoblastic leukaemia; AML acute myeloid leukaemia; HEI healthy eating index; Childhood leukaemia; Diet quality; Epidemiology; Prenatal nutrition
- Accession Number:
0 (Vitamins)
- Publication Date:
Date Created: 20161012 Date Completed: 20170519 Latest Revision: 20220310
- Publication Date:
20231215
- Accession Number:
10.1017/S0007114516003469
- Accession Number:
27725005
No Comments.